Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2 FamilyCystathionine synthase-like 8059630 4000672 SCOP2 (2022-06-29)
ASCOP2 SuperfamilyPLP-dependent transferases 8059631 3000954 SCOP2 (2022-06-29)
BSCOP2B SuperfamilyPLP-dependent transferases 8059631 3000954 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyPLP-dependent transferases 8059631 3000954 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyPLP-dependent transferases 8059631 3000954 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
ACys_Met_Meta_PP_Ce3ndnA3 A: a+b two layersX: C-terminal domain in some PLP-dependent transferases (From Topology)H: C-terminal domain in some PLP-dependent transferases (From Topology)T: C-terminal domain in some PLP-dependent transferasesF: Cys_Met_Meta_PP_CECOD (1.6)
ACys_Met_Meta_PP_Ne3ndnA2 A: a/b three-layered sandwichesX: PLP-dependent transferases (From Topology)H: PLP-dependent transferases (From Topology)T: PLP-dependent transferasesF: Cys_Met_Meta_PP_NECOD (1.6)
BCys_Met_Meta_PP_Ce3ndnB3 A: a+b two layersX: C-terminal domain in some PLP-dependent transferases (From Topology)H: C-terminal domain in some PLP-dependent transferases (From Topology)T: C-terminal domain in some PLP-dependent transferasesF: Cys_Met_Meta_PP_CECOD (1.6)
BCys_Met_Meta_PP_Ne3ndnB2 A: a/b three-layered sandwichesX: PLP-dependent transferases (From Topology)H: PLP-dependent transferases (From Topology)T: PLP-dependent transferasesF: Cys_Met_Meta_PP_NECOD (1.6)
CCys_Met_Meta_PP_Ce3ndnC3 A: a+b two layersX: C-terminal domain in some PLP-dependent transferases (From Topology)H: C-terminal domain in some PLP-dependent transferases (From Topology)T: C-terminal domain in some PLP-dependent transferasesF: Cys_Met_Meta_PP_CECOD (1.6)
CCys_Met_Meta_PP_Ne3ndnC2 A: a/b three-layered sandwichesX: PLP-dependent transferases (From Topology)H: PLP-dependent transferases (From Topology)T: PLP-dependent transferasesF: Cys_Met_Meta_PP_NECOD (1.6)
DCys_Met_Meta_PP_Ce3ndnD3 A: a+b two layersX: C-terminal domain in some PLP-dependent transferases (From Topology)H: C-terminal domain in some PLP-dependent transferases (From Topology)T: C-terminal domain in some PLP-dependent transferasesF: Cys_Met_Meta_PP_CECOD (1.6)
DCys_Met_Meta_PP_Ne3ndnD2 A: a/b three-layered sandwichesX: PLP-dependent transferases (From Topology)H: PLP-dependent transferases (From Topology)T: PLP-dependent transferasesF: Cys_Met_Meta_PP_NECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B, C, D
PF01053Cys/Met metabolism PLP-dependent enzyme (Cys_Met_Meta_PP)Cys/Met metabolism PLP-dependent enzymeThis family includes enzymes involved in cysteine and methionine metabolism. The following are members: Cystathionine gamma-lyase, Cystathionine gamma-synthase, Cystathionine beta-lyase, Methionine gamma-lyase, OAH/OAS sulfhydrylase, O-succinylhomos ...This family includes enzymes involved in cysteine and methionine metabolism. The following are members: Cystathionine gamma-lyase, Cystathionine gamma-synthase, Cystathionine beta-lyase, Methionine gamma-lyase, OAH/OAS sulfhydrylase, O-succinylhomoserine sulfhydrylase All of these members participate is slightly different reactions. All these enzymes use PLP (pyridoxal-5'-phosphate) as a cofactor.
Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B, C, D
O-succinylhomoserine sulfhydrylase

Protein Modification Annotation

Modified Residue(s)
ChainResidue(s)Description
A, B, C, D
LLP Parent Component: LYS

RESIDAA0119

PSI-MOD :  N6-pyridoxal phosphate-L-lysine MOD:00128