Annotations: 3NVD

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Glyco_hydro_3	e3nvdA1	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: Glyco_hydro_3	ECOD (1.6)
A	Glyco_hydro_3_C	e3nvdA2	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: Beta-D-glucan exohydrolase, C-terminal domain (From Topology)	T: Beta-D-glucan exohydrolase, C-terminal domain	F: Glyco_hydro_3_C	ECOD (1.6)
B	Glyco_hydro_3	e3nvdB1	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: Glyco_hydro_3	ECOD (1.6)
B	Glyco_hydro_3_C	e3nvdB2	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: Beta-D-glucan exohydrolase, C-terminal domain (From Topology)	T: Beta-D-glucan exohydrolase, C-terminal domain	F: Glyco_hydro_3_C	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.20.20.300	Alpha Beta	Alpha-Beta Barrel	TIM Barrel	Glycoside hydrolase, family 3, N-terminal domain	CATH (4.3.0)
A	3.40.50.1700	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Glycoside hydrolase family 3 C-terminal domain	CATH (4.3.0)
B	3.20.20.300	Alpha Beta	Alpha-Beta Barrel	TIM Barrel	Glycoside hydrolase, family 3, N-terminal domain	CATH (4.3.0)
B	3.40.50.1700	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Glycoside hydrolase family 3 C-terminal domain	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF00933	Glycosyl hydrolase family 3 N terminal domain (Glyco_hydro_3)	Glycosyl hydrolase family 3 N terminal domain	-	Domain
A, B	PF01915	Glycosyl hydrolase family 3 C-terminal domain (Glyco_hydro_3_C)	Glycosyl hydrolase family 3 C-terminal domain	This domain is involved in catalysis and may be involved in binding beta-glucan [1]. This domain is found associated with Pfam:PF00933.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Uncharacterized lipoprotein ybbD	hydrolase activity, acting on glycosyl bonds hexosaminidase activity beta-N-acetylhexosaminidase activity hydrolase activity, hydrolyzing O-glycosyl compounds hydrolase activity catalytic activity	developmental process regulation of biological process regulation of developmental process biological regulation regulation of cell shape cell morphogenesis regulation of cell morphogenesis anatomical structure morphogenesis anatomical structure development regulation of biological quality regulation of anatomical structure morphogenesis carbohydrate metabolic process primary metabolic process metabolic process developmental process regulation of biological process regulation of developmental process biological regulation regulation of cell shape cell morphogenesis regulation of cell morphogenesis anatomical structure morphogenesis anatomical structure development regulation of biological quality regulation of anatomical structure morphogenesis carbohydrate metabolic process primary metabolic process metabolic process cellular process cellular component organization cell wall organization or biogenesis cell wall organization cellular component organization or biogenesis external encapsulating structure organization carbohydrate derivative biosynthetic process peptidoglycan-based cell wall biogenesis glycosaminoglycan metabolic process carbohydrate derivative metabolic process macromolecule biosynthetic process cellular component biogenesis peptidoglycan biosynthetic process cell wall biogenesis biosynthetic process cell wall macromolecule biosynthetic process aminoglycan metabolic process peptidoglycan metabolic process aminoglycan biosynthetic process glycosaminoglycan biosynthetic process macromolecule metabolic process peptidoglycan turnover	cellular anatomical structure extracellular region cell periphery plasma membrane membrane

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR001764	Glycoside hydrolase, family 3, N-terminal	Domain
A, B	IPR017853	Glycoside hydrolase superfamily	Homologous Superfamily
A, B	IPR002772	Glycoside hydrolase family 3 C-terminal domain	Domain
A, B	IPR036962	Glycoside hydrolase, family 3, N-terminal domain superfamily	Homologous Superfamily
A, B	IPR050226	NagZ Beta-hexosaminidase	Family
A, B	IPR019800	Glycoside hydrolase, family 3, active site	Active Site
A, B	IPR036881	Glycoside hydrolase family 3 C-terminal domain superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.