Annotations: 3STD

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d3stda_	Alpha and beta proteins (a+b)	Cystatin-like	NTF2-like	Scytalone dehydratase	Scytalone dehydratase	(Pyricularia grisea ) [TaxId: 148305 ],	SCOPe (2.08)
B	d3stdb_	Alpha and beta proteins (a+b)	Cystatin-like	NTF2-like	Scytalone dehydratase	Scytalone dehydratase	(Pyricularia grisea ) [TaxId: 148305 ],	SCOPe (2.08)
C	d3stdc_	Alpha and beta proteins (a+b)	Cystatin-like	NTF2-like	Scytalone dehydratase	Scytalone dehydratase	(Pyricularia grisea ) [TaxId: 148305 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	NTF2-like	8044551	3000472	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	NTF2-like	8044551	3000472	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	NTF2-like	8044551	3000472	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Scytalone_dh	e3stdA1	A: a+b two layers	X: Cystatin-like	H: NTF2-like (From Topology)	T: NTF2-like	F: Scytalone_dh	ECOD (1.6)
B	Scytalone_dh	e3stdB1	A: a+b two layers	X: Cystatin-like	H: NTF2-like (From Topology)	T: NTF2-like	F: Scytalone_dh	ECOD (1.6)
C	Scytalone_dh	e3stdC1	A: a+b two layers	X: Cystatin-like	H: NTF2-like (From Topology)	T: NTF2-like	F: Scytalone_dh	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.10.450.50	Alpha Beta	Roll	Nuclear Transport Factor 2	Chain: A,	CATH (4.3.0)
B	3.10.450.50	Alpha Beta	Roll	Nuclear Transport Factor 2	Chain: A,	CATH (4.3.0)
C	3.10.450.50	Alpha Beta	Roll	Nuclear Transport Factor 2	Chain: A,	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C	PF02982	Scytalone dehydratase (Scytalone_dh)	Scytalone dehydratase	Scytalone dehydratases are structurally related to the NTF2 family (see Pfam:PF02136).	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C	PROTEIN (SCYTALONE DEHYDRATASE)	cation binding ion binding binding metal ion binding small molecule binding scytalone dehydratase activity hydro-lyase activity lyase activity catalytic activity carbon-oxygen lyase activity	pigment metabolic process organic hydroxy compound metabolic process pigment biosynthetic process melanin metabolic process secondary metabolic process biosynthetic process secondary metabolite biosynthetic process organic hydroxy compound biosynthetic process phenol-containing compound metabolic process phenol-containing compound biosynthetic process metabolic process melanin biosynthetic process	membrane-bounded organelle intracellular anatomical structure endosome intracellular vesicle cellular anatomical entity intracellular membrane-bounded organelle endomembrane system intracellular organelle cytoplasmic vesicle organelle cytoplasm vesicle

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C	IPR032710	NTF2-like domain superfamily	Homologous Superfamily
A, B, C	IPR004235	Scytalone dehydratase	Family
A, B, C	IPR049884	Scytalone dehydratase-like	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.