Annotations: 3TIG

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d3tiga1	Alpha and beta proteins (a/b)	PreATP-grasp domain	PreATP-grasp domain	Tubulin tyrosine ligase (TTL) N-terminal domain-like	Tubulin tyrosine ligase (TTL) N-terminal domain	Western clawed frog (Xenopus tropicalis ) [TaxId: 8364 ],	SCOPe (2.08)
A	d3tiga3	Alpha and beta proteins (a+b)	ATP-grasp	Glutathione synthetase ATP-binding domain-like	Tubulin tyrosine ligase (TTL) C-terminal domain-like	Tubulin tyrosine ligase (TTL) C-terminal domain	Western clawed frog (Xenopus tropicalis ) [TaxId: 8364 ],	SCOPe (2.08)
A	d3tiga2	Artifacts	Tags	Tags	Tags	N-terminal Tags	Western clawed frog (Xenopus tropicalis ) [TaxId: 8364 ],	SCOPe (2.08)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	TTL	e3tigA1	A: a+b complex topology	X: Protein kinase/SAICAR synthase/ATP-grasp (From Homology)	H: Protein kinase/SAICAR synthase/ATP-grasp	T: ATP-grasp	F: TTL	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.50.11480	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold		CATH (4.3.0)
A	3.30.470.20	Alpha Beta	2-Layer Sandwich	D-amino Acid Aminotransferase	Chain A, domain 1	CATH (4.3.0)
A	3.30.1490.20	Alpha Beta	2-Layer Sandwich	Dna Ligase	domain 1	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF03133	Tubulin-tyrosine ligase family (TTL)	Tubulin-tyrosine ligase family	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Ttl protein	catalytic activity ligase activity binding nucleoside phosphate binding organic cyclic compound binding nucleotide binding heterocyclic compound binding small molecule binding cation binding ion binding metal ion binding	macromolecule modification metabolic process primary metabolic process protein metabolic process macromolecule metabolic process protein modification process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR052492	Tubulin--tyrosine ligase	Family
A	IPR004344	Tubulin-tyrosine ligase/Tubulin polyglutamylase	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.