3UAZ

Crystal structure of Bacillus cereus adenosine phosphorylase D204N mutant complexed with inosine

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d3uaza_	Alpha and beta proteins (a/b)	Phosphorylase/hydrolase-like	Purine and uridine phosphorylases	Purine and uridine phosphorylases	Purine nucleoside phosphorylase, PNP	(Bacillus cereus ) [TaxId: 1396 ],	SCOPe (2.08)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PNP_UDP_1	e3uazA2	A: a/b three-layered sandwiches	X: Phosphorylase/hydrolase-like	H: Peptidyl-tRNA hydrolase-like (From Topology)	T: Peptidyl-tRNA hydrolase-like	F: PNP_UDP_1	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.50.1580	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Nucleoside phosphorylase domain	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF01048	Phosphorylase superfamily (PNP_UDP_1)	Phosphorylase superfamily	Members of this family include: purine nucleoside phosphorylase (PNP) Uridine phosphorylase (UdRPase) 5'-methylthioadenosine phosphorylase (MTA phosphorylase)	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Purine nucleoside phosphorylase deoD-type	pentosyltransferase activity glycosyltransferase activity purine-nucleoside phosphorylase activity transferase activity catalytic activity	glycosyl compound metabolic process carbohydrate derivative metabolic process primary metabolic process nucleoside metabolic process purine-containing compound metabolic process nucleobase-containing compound metabolic process nucleobase-containing small molecule metabolic process metabolic process cellular process small molecule metabolic process purine nucleoside metabolic process carbohydrate derivative catabolic process catabolic process glycosyl compound catabolic process glycosyl compound metabolic process carbohydrate derivative metabolic process primary metabolic process nucleoside metabolic process purine-containing compound metabolic process nucleobase-containing compound metabolic process nucleobase-containing small molecule metabolic process metabolic process cellular process small molecule metabolic process purine nucleoside metabolic process carbohydrate derivative catabolic process catabolic process glycosyl compound catabolic process nucleobase-containing compound catabolic process nucleobase-containing small molecule catabolic process nucleoside catabolic process small molecule catabolic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR018016	Nucleoside phosphorylase, conserved site	Conserved Site
A	IPR004402	Purine nucleoside phosphorylase DeoD-type	Family
A	IPR035994	Nucleoside phosphorylase superfamily	Homologous Superfamily
A	IPR000845	Nucleoside phosphorylase domain	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.