Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AEUF08614e4bqoA1 A: a/b three-layered sandwichesX: Flavodoxin-likeH: Polysaccharide biosynthesis enzyme WcbI (From Topology)T: Polysaccharide biosynthesis enzyme WcbIF: EUF08614ECOD (1.6)
BEUF08614e4bqoB1 A: a/b three-layered sandwichesX: Flavodoxin-likeH: Polysaccharide biosynthesis enzyme WcbI (From Topology)T: Polysaccharide biosynthesis enzyme WcbIF: EUF08614ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A3.40.50.12080 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold CATH (4.3.0)
A1.10.10.2490 Mainly Alpha Orthogonal Bundle Arc Repressor Mutant, subunit A CATH (4.3.0)
B3.40.50.12080 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold CATH (4.3.0)
B1.10.10.2490 Mainly Alpha Orthogonal Bundle Arc Repressor Mutant, subunit A CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B
PF18588Polysaccharide biosynthesis enzyme WcbI (WcbI)Polysaccharide biosynthesis enzyme WcbICapsular polysaccharides (CPSs) are protective structures on the surfaces of many Gram-negative bacteria. wcbI is one of several genes in the CPS biosynthetic cluster whose deletion leads to significant attenuation of the pathogen. Structural analysi ...Capsular polysaccharides (CPSs) are protective structures on the surfaces of many Gram-negative bacteria. wcbI is one of several genes in the CPS biosynthetic cluster whose deletion leads to significant attenuation of the pathogen. Structural analysis and biophysical assays suggest that WcbI functions as an acetyltransferase enzyme but it requires another functional module to carry out this function. WcbI adopts a predominantly helical fold where the N-terminal 100 amino acids form a ligand-binding domain and binds tightly to coenzyme A and its derivative acetyl-CoA [1].
Domain

InterPro: Protein Family Classification InterPro Database Homepage