Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B SuperfamilyDihydropteroate synthetase-like 8043870 3000643 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyDihydropteroate synthetase-like 8043870 3000643 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyAcsC C-terminal domain-like 8089872 3002396 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyDihydropteroate synthetase-like 8089870 3000643 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyAcsC Fe-S domain-like 8089862 3002395 SCOP2B (2022-06-29)
ESCOP2B SuperfamilyDihydropteroate synthetase-like 8089870 3000643 SCOP2B (2022-06-29)
ESCOP2B SuperfamilyAcsC Fe-S domain-like 8089862 3002395 SCOP2B (2022-06-29)
ESCOP2B SuperfamilyAcsC C-terminal domain-like 8089872 3002396 SCOP2B (2022-06-29)
FSCOP2B SuperfamilyDihydropteroate synthetase-like 8089873 3000643 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyDihydropteroate synthetase-like 8089873 3000643 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
APterin_binde4djeA1 A: a/b barrelsX: TIM beta/alpha-barrelH: TIM barrels (From Topology)T: TIM barrelsF: Pterin_bindECOD (1.6)
BPterin_binde4djeB1 A: a/b barrelsX: TIM beta/alpha-barrelH: TIM barrels (From Topology)T: TIM barrelsF: Pterin_bindECOD (1.6)
CCdhD_Ne4djeC4 A: a/b barrelsX: TIM beta/alpha-barrelH: TIM barrels (From Topology)T: TIM barrelsF: CdhD_NECOD (1.6)
CCdhD_Ce4djeC1 A: a/b three-layered sandwichesX: B12 binding domain in carbon monoxide dehydrogenase corrinoid/iron-sulfur protein gamma subunit (From Topology)H: B12 binding domain in carbon monoxide dehydrogenase corrinoid/iron-sulfur protein gamma subunit (From Topology)T: B12 binding domain in carbon monoxide dehydrogenase corrinoid/iron-sulfur protein gamma subunitF: CdhD_CECOD (1.6)
CFeSe4djeC3 A: few secondary structure elementsX: Fe-S cluster binding domain in carbon monoxide dehydrogenase corrinoid/iron-sulfur protein gamma subunit (From Topology)H: Fe-S cluster binding domain in carbon monoxide dehydrogenase corrinoid/iron-sulfur protein gamma subunit (From Topology)T: Fe-S cluster binding domain in carbon monoxide dehydrogenase corrinoid/iron-sulfur protein gamma subunitF: FeSECOD (1.6)
ECdhD_Ne4djeE4 A: a/b barrelsX: TIM beta/alpha-barrelH: TIM barrels (From Topology)T: TIM barrelsF: CdhD_NECOD (1.6)
ECdhD_Ce4djeE1 A: a/b three-layered sandwichesX: B12 binding domain in carbon monoxide dehydrogenase corrinoid/iron-sulfur protein gamma subunit (From Topology)H: B12 binding domain in carbon monoxide dehydrogenase corrinoid/iron-sulfur protein gamma subunit (From Topology)T: B12 binding domain in carbon monoxide dehydrogenase corrinoid/iron-sulfur protein gamma subunitF: CdhD_CECOD (1.6)
EFeSe4djeE3 A: few secondary structure elementsX: Fe-S cluster binding domain in carbon monoxide dehydrogenase corrinoid/iron-sulfur protein gamma subunit (From Topology)H: Fe-S cluster binding domain in carbon monoxide dehydrogenase corrinoid/iron-sulfur protein gamma subunit (From Topology)T: Fe-S cluster binding domain in carbon monoxide dehydrogenase corrinoid/iron-sulfur protein gamma subunitF: FeSECOD (1.6)
FCdhD_Ne4djeF1 A: a/b barrelsX: TIM beta/alpha-barrelH: TIM barrels (From Topology)T: TIM barrelsF: CdhD_NECOD (1.6)
DCdhD_Ne4djeD1 A: a/b barrelsX: TIM beta/alpha-barrelH: TIM barrels (From Topology)T: TIM barrelsF: CdhD_NECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B
PF00809Pterin binding enzyme (Pterin_bind)Pterin binding enzymeThis family includes a variety of pterin binding enzymes that all adopt a TIM barrel fold. The family includes dihydropteroate synthase EC:2.5.1.15 as well as a group methyltransferase enzymes including methyltetrahydrofolate, corrinoid iron-sulfur p ...This family includes a variety of pterin binding enzymes that all adopt a TIM barrel fold. The family includes dihydropteroate synthase EC:2.5.1.15 as well as a group methyltransferase enzymes including methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) Swiss:Q46389 that catalyses a key step in the Wood-Ljungdahl pathway of carbon dioxide fixation. It transfers the N5-methyl group from methyltetrahydrofolate (CH3-H4folate) to a cob(I)amide centre in another protein, the corrinoid iron-sulfur protein. MeTr is a member of a family of proteins that includes methionine synthase and methanogenic enzymes that activate the methyl group of methyltetra-hydromethano(or -sarcino)pterin [2].
Domain
C, E
PF04060Putative Fe-S cluster (FeS)Putative Fe-S clusterThis family includes a domain with four conserved cysteines that probably form an Fe-S redox cluster.Domain
C, E
PF03599CO dehydrogenase/acetyl-CoA synthase delta subunit (CdhD)CO dehydrogenase/acetyl-CoA synthase delta subunit- Family
D, F
PF03599CO dehydrogenase/acetyl-CoA synthase delta subunit (CdhD)CO dehydrogenase/acetyl-CoA synthase delta subunit- Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B
5-methyltetrahydrofolate corrinoid/iron sulfur protein methyltransferase
C, E
Corrinoid/iron-sulfur protein large subunit -
D, F
Corrinoid/iron-sulfur protein small subunit -