4DJE
Crystal structure of folate-bound corrinoid iron-sulfur protein (CFeSP) in complex with its methyltransferase (MeTr), co-crystallized with folate
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
A | SCOP2B Superfamily | Dihydropteroate synthetase-like | 8043870 | 3000643 | SCOP2B (2022-06-29) |
B | SCOP2B Superfamily | Dihydropteroate synthetase-like | 8043870 | 3000643 | SCOP2B (2022-06-29) |
C | SCOP2B Superfamily | AcsC C-terminal domain-like | 8089872 | 3002396 | SCOP2B (2022-06-29) |
C | SCOP2B Superfamily | Dihydropteroate synthetase-like | 8089870 | 3000643 | SCOP2B (2022-06-29) |
C | SCOP2B Superfamily | AcsC Fe-S domain-like | 8089862 | 3002395 | SCOP2B (2022-06-29) |
E | SCOP2B Superfamily | Dihydropteroate synthetase-like | 8089870 | 3000643 | SCOP2B (2022-06-29) |
E | SCOP2B Superfamily | AcsC Fe-S domain-like | 8089862 | 3002395 | SCOP2B (2022-06-29) |
E | SCOP2B Superfamily | AcsC C-terminal domain-like | 8089872 | 3002396 | SCOP2B (2022-06-29) |
F | SCOP2B Superfamily | Dihydropteroate synthetase-like | 8089873 | 3000643 | SCOP2B (2022-06-29) |
D | SCOP2B Superfamily | Dihydropteroate synthetase-like | 8089873 | 3000643 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | Pterin_bind | e4djeA1 | A: a/b barrels | X: TIM beta/alpha-barrel | H: TIM barrels (From Topology) | T: TIM barrels | F: Pterin_bind | ECOD (1.6) |
B | Pterin_bind | e4djeB1 | A: a/b barrels | X: TIM beta/alpha-barrel | H: TIM barrels (From Topology) | T: TIM barrels | F: Pterin_bind | ECOD (1.6) |
C | CdhD_N | e4djeC4 | A: a/b barrels | X: TIM beta/alpha-barrel | H: TIM barrels (From Topology) | T: TIM barrels | F: CdhD_N | ECOD (1.6) |
C | CdhD_C | e4djeC1 | A: a/b three-layered sandwiches | X: B12 binding domain in carbon monoxide dehydrogenase corrinoid/iron-sulfur protein gamma subunit (From Topology) | H: B12 binding domain in carbon monoxide dehydrogenase corrinoid/iron-sulfur protein gamma subunit (From Topology) | T: B12 binding domain in carbon monoxide dehydrogenase corrinoid/iron-sulfur protein gamma subunit | F: CdhD_C | ECOD (1.6) |
C | FeS | e4djeC3 | A: few secondary structure elements | X: Fe-S cluster binding domain in carbon monoxide dehydrogenase corrinoid/iron-sulfur protein gamma subunit (From Topology) | H: Fe-S cluster binding domain in carbon monoxide dehydrogenase corrinoid/iron-sulfur protein gamma subunit (From Topology) | T: Fe-S cluster binding domain in carbon monoxide dehydrogenase corrinoid/iron-sulfur protein gamma subunit | F: FeS | ECOD (1.6) |
E | CdhD_N | e4djeE4 | A: a/b barrels | X: TIM beta/alpha-barrel | H: TIM barrels (From Topology) | T: TIM barrels | F: CdhD_N | ECOD (1.6) |
E | CdhD_C | e4djeE1 | A: a/b three-layered sandwiches | X: B12 binding domain in carbon monoxide dehydrogenase corrinoid/iron-sulfur protein gamma subunit (From Topology) | H: B12 binding domain in carbon monoxide dehydrogenase corrinoid/iron-sulfur protein gamma subunit (From Topology) | T: B12 binding domain in carbon monoxide dehydrogenase corrinoid/iron-sulfur protein gamma subunit | F: CdhD_C | ECOD (1.6) |
E | FeS | e4djeE3 | A: few secondary structure elements | X: Fe-S cluster binding domain in carbon monoxide dehydrogenase corrinoid/iron-sulfur protein gamma subunit (From Topology) | H: Fe-S cluster binding domain in carbon monoxide dehydrogenase corrinoid/iron-sulfur protein gamma subunit (From Topology) | T: Fe-S cluster binding domain in carbon monoxide dehydrogenase corrinoid/iron-sulfur protein gamma subunit | F: FeS | ECOD (1.6) |
F | CdhD_N | e4djeF1 | A: a/b barrels | X: TIM beta/alpha-barrel | H: TIM barrels (From Topology) | T: TIM barrels | F: CdhD_N | ECOD (1.6) |
D | CdhD_N | e4djeD1 | A: a/b barrels | X: TIM beta/alpha-barrel | H: TIM barrels (From Topology) | T: TIM barrels | F: CdhD_N | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A | 3.20.20.20 | Alpha Beta | Alpha-Beta Barrel | TIM Barrel | Dihydropteroate synthase-like | CATH (4.3.0) |
B | 3.20.20.20 | Alpha Beta | Alpha-Beta Barrel | TIM Barrel | Dihydropteroate synthase-like | CATH (4.3.0) |
C | 3.20.20.20 | Alpha Beta | Alpha-Beta Barrel | TIM Barrel | Dihydropteroate synthase-like | CATH (4.3.0) |
C | 3.40.50.11600 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | CATH (4.3.0) | |
E | 3.20.20.20 | Alpha Beta | Alpha-Beta Barrel | TIM Barrel | Dihydropteroate synthase-like | CATH (4.3.0) |
E | 3.40.50.11600 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | CATH (4.3.0) | |
F | 3.20.20.20 | Alpha Beta | Alpha-Beta Barrel | TIM Barrel | Dihydropteroate synthase-like | CATH (4.3.0) |
D | 3.20.20.20 | Alpha Beta | Alpha-Beta Barrel | TIM Barrel | Dihydropteroate synthase-like | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF00809 | Pterin binding enzyme (Pterin_bind) | Pterin binding enzyme | This family includes a variety of pterin binding enzymes that all adopt a TIM barrel fold. The family includes dihydropteroate synthase EC:2.5.1.15 as well as a group methyltransferase enzymes including methyltetrahydrofolate, corrinoid iron-sulfur p ... | Domain | |
PF04060 | Putative Fe-S cluster (FeS) | Putative Fe-S cluster | This family includes a domain with four conserved cysteines that probably form an Fe-S redox cluster. | Domain | |
PF03599 | CO dehydrogenase/acetyl-CoA synthase delta subunit (CdhD) | CO dehydrogenase/acetyl-CoA synthase delta subunit | - | Family | |
PF03599 | CO dehydrogenase/acetyl-CoA synthase delta subunit (CdhD) | CO dehydrogenase/acetyl-CoA synthase delta subunit | - | Family |