4FKZ

Crystal structure of Bacillus subtilis UDP-GlcNAc 2-epimerase in complex with UDP-GlcNAc and UDP

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d4fkza1	Alpha and beta proteins (a/b)	UDP-Glycosyltransferase/glycogen phosphorylase	UDP-Glycosyltransferase/glycogen phosphorylase	UDP-N-acetylglucosamine 2-epimerase	automated matches	(Bacillus subtilis subsp. subtilis str. 168 ) [TaxId: 224308 ],	SCOPe (2.08)
A	d4fkza2	Artifacts	Tags	Tags	Tags	C-terminal Tags	(Bacillus subtilis subsp. subtilis str. 168 ) [TaxId: 224308 ],	SCOPe (2.08)
B	d4fkzb_	Alpha and beta proteins (a/b)	UDP-Glycosyltransferase/glycogen phosphorylase	UDP-Glycosyltransferase/glycogen phosphorylase	UDP-N-acetylglucosamine 2-epimerase	automated matches	(Bacillus subtilis subsp. subtilis str. 168 ) [TaxId: 224308 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Type B glycosyltransferase-like	8037295	3001586	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Type B glycosyltransferase-like	8037295	3001586	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Epimerase_2_C	e4fkzA1	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: Epimerase_2_C	ECOD (1.6)
A	Epimerase_2_N	e4fkzA2	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: Epimerase_2_N	ECOD (1.6)
B	Epimerase_2_C	e4fkzB2	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: Epimerase_2_C	ECOD (1.6)
B	Epimerase_2_N	e4fkzB1	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: Epimerase_2_N	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.50.2000	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Glycogen Phosphorylase B	CATH (4.3.0)
B	3.40.50.2000	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Glycogen Phosphorylase B	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF02350	UDP-N-acetylglucosamine 2-epimerase (Epimerase_2)	UDP-N-acetylglucosamine 2-epimerase	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	UDP-N-acetylglucosamine 2-epimerase	isomerase activity racemase and epimerase activity UDP-N-acetylglucosamine 2-epimerase activity racemase and epimerase activity, acting on carbohydrates and derivatives catalytic activity	carbohydrate derivative biosynthetic process teichoic acid biosynthetic process peptidoglycan-based cell wall biogenesis small molecule biosynthetic process cell wall organization or biogenesis carbohydrate derivative metabolic process organic acid biosynthetic process organic acid metabolic process macromolecule biosynthetic process cellular component biogenesis cell wall biogenesis biosynthetic process cell wall macromolecule biosynthetic process cellular process carbohydrate derivative biosynthetic process teichoic acid biosynthetic process peptidoglycan-based cell wall biogenesis small molecule biosynthetic process cell wall organization or biogenesis carbohydrate derivative metabolic process organic acid biosynthetic process organic acid metabolic process macromolecule biosynthetic process cellular component biogenesis cell wall biogenesis biosynthetic process cell wall macromolecule biosynthetic process cellular process metabolic process small molecule metabolic process cellular component organization or biogenesis macromolecule metabolic process teichoic acid metabolic process cellular component organization cell wall organization external encapsulating structure organization	cellular anatomical structure intracellular anatomical structure cytoplasm

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR003331	UDP-N-acetylglucosamine 2-epimerase domain	Domain
A, B	IPR029767	UDP-N-acetylglucosamine 2-epimerase WecB-like	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.