Annotations: 4HNW

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
B	SCOP2B Superfamily	Acyl-CoA N-acyltransferases (Nat)	8101495	3000403	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	TPR_15	e4hnwA1	A: alpha superhelices	X: Repetitive alpha hairpins	H: ARM repeat (From Topology)	T: ARM repeat	F: TPR_15	ECOD (1.6)
B	Acetyltransf_10_5	e4hnwB1	A: a+b three layers	X: Nat/Ivy	H: Acyl-CoA N-acyltransferases (Nat) (From Topology)	T: Acyl-CoA N-acyltransferases (Nat)	F: Acetyltransf_10_5	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
B	3.40.630.30	Alpha Beta	3-Layer(aba) Sandwich	Aminopeptidase	Gcn5-related N-acetyltransferase (GNAT)	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF12569	N-terminal acetyltransferase A, auxiliary subunit (NatA_aux_su)	N-terminal acetyltransferase A, auxiliary subunit	-	Repeat
B	PF00583	Acetyltransferase (GNAT) family (Acetyltransf_1)	Acetyltransferase (GNAT) family	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	N-terminal acetyltransferase A complex subunit NAT1	ribonucleoprotein complex binding protein-containing complex binding binding ribosome binding	-	membrane-bounded organelle intracellular organelle intracellular anatomical structure mitochondrion organelle cytoplasm cellular anatomical entity intracellular membrane-bounded organelle protein-containing complex NatA complex catalytic complex N-terminal protein acetyltransferase complex transferase complex acetyltransferase complex membrane-bounded organelle intracellular organelle intracellular anatomical structure mitochondrion organelle cytoplasm cellular anatomical entity intracellular membrane-bounded organelle protein-containing complex NatA complex catalytic complex N-terminal protein acetyltransferase complex transferase complex acetyltransferase complex protein acetyltransferase complex intracellular protein-containing complex
B	N-terminal acetyltransferase A complex catalytic subunit ARD1	acetyltransferase activity N-acetyltransferase activity acyltransferase activity peptide-serine-alpha-N-acetyltransferase activity peptide alpha-N-acetyltransferase activity acyltransferase activity, transferring groups other than amino-acyl groups transferase activity peptide N-acetyltransferase activity catalytic activity N-acyltransferase activity peptide-glutamate-alpha-N-acetyltransferase activity identical protein binding protein binding binding	-	protein-containing complex intracellular anatomical structure NatA complex catalytic complex N-terminal protein acetyltransferase complex cellular anatomical entity transferase complex acetyltransferase complex protein acetyltransferase complex cytoplasm intracellular protein-containing complex

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR021183	N-terminal acetyltransferase A, auxiliary subunit	Family
A	IPR011990	Tetratricopeptide-like helical domain superfamily	Homologous Superfamily
A	IPR019734	Tetratricopeptide repeat	Repeat
B	IPR045047	N-acetyltransferase Ard1-like	Family
B	IPR016181	Acyl-CoA N-acyltransferase	Homologous Superfamily
B	IPR000182	GNAT domain	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.