Crystal Structure Of AKR1B10 Complexed With NADP+ And Epalrestat
External Resource: Annotation
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
A | SCOP2B Superfamily | NAD(P)-linked oxidoreductase | 8061987 | 3000288 | SCOP2B (2022-06-29) |
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
A | Aldo_ket_red | e4jihA1 | A: a/b barrels | X: TIM beta/alpha-barrel | H: TIM barrels (From Topology) | T: TIM barrels | F: Aldo_ket_red | ECOD (1.6) |
Chains | Accession | Name | Description | Comments | Source |
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| PF00248 | Aldo/keto reductase family (Aldo_ket_red) | Aldo/keto reductase family | This family includes a number of K+ ion channel beta chain regulatory domains - these are reported to have oxidoreductase activity [2]. | Domain |
Chains | Polymer | Molecular Function | Biological Process | Cellular Component |
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| Aldo-keto reductase family 1 member B10 | | | |
Chains | Drug Target   | Associated Disease |
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| Pharos:  O60218 | |
Protein Modification Annotation
Modified Residue(s) |
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Chain | Residue(s) | Description |
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| CSO | Parent Component: CYS
RESID:  AA0205
PSI-MOD :  L-cysteine sulfenic acid MOD:00210 |