Crystal structure of Anti-IL-17A antibody CNTO7357
External Resource: Annotation
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
A [auth L] | d4kq4l2 | All beta proteins | Immunoglobulin-like beta-sandwich | Immunoglobulin | C1 set domains (antibody constant domain-like) | automated matches | mouse (Mus musculus ) [TaxId: 10090 ], human (Homo sapiens ) [TaxId: 9606 ], | SCOPe (2.08) |
A [auth L] | d4kq4l1 | All beta proteins | Immunoglobulin-like beta-sandwich | Immunoglobulin | automated matches | automated matches | mouse (Mus musculus ) [TaxId: 10090 ], human (Homo sapiens ) [TaxId: 9606 ], | SCOPe (2.08) |
B [auth H] | d4kq4h1 | All beta proteins | Immunoglobulin-like beta-sandwich | Immunoglobulin | automated matches | automated matches | mouse (Mus musculus ) [TaxId: 10090 ], human (Homo sapiens ) [TaxId: 9606 ], | SCOPe (2.08) |
B [auth H] | d4kq4h3 | Artifacts | Tags | Tags | Tags | C-terminal Tags | mouse (Mus musculus ) [TaxId: 10090 ], human (Homo sapiens ) [TaxId: 9606 ], | SCOPe (2.08) |
B [auth H] | d4kq4h2 | Artifacts | Tags | Tags | Tags | N-terminal Tags | mouse (Mus musculus ) [TaxId: 10090 ], human (Homo sapiens ) [TaxId: 9606 ], | SCOPe (2.08) |
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
A [auth L] | C1-set_4 | e4kq4L1 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: C1-set_4 | ECOD (1.6) |
A [auth L] | V-set | e4kq4L2 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: V-set | ECOD (1.6) |
B [auth H] | V-set_8 | e4kq4H2 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: V-set_8 | ECOD (1.6) |
B [auth H] | C1-set_1 | e4kq4H1 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: C1-set_1 | ECOD (1.6) |
Chain | Protein Name | Description | Organism Name | Gene Allele Name(s) | Domain Name(s) | Receptor Type | Receptor Description | Provenance Source |
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A [auth L] | CNTO7357 Fab | L-KAPPA | Chimeric (chimeric) | IGKV6-25*01, IGKJ2*01, IGKC*01 | V-DOMAIN V-KAPPA, C-DOMAIN C-KAPPA | IG | FAB-GAMMA-1_KAPPA | IMGT (202446-0) |
B [auth H] | CNTO7357 Fab | VH-CH1 | Chimeric (chimeric) | IGHV1S137*01, IGHJ4*01, IGHG1*01, IGHG1*02, IGHG1*04 | V-DOMAIN VH, C-DOMAIN CH1 | IG | FAB-GAMMA-1_KAPPA | IMGT (202446-0) |
Chain | Chain Class | Chain Subclass | Chain Type | Antigen Name(s) | Provenance Source |
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A [auth L] | Light Chain | IGKV6 | Kappa | - | SAbDab (2024-11-15) |
B [auth H] | Heavy Chain | IGHV1 | - | - | SAbDab (2024-11-15) |