4R6Q

Jacalin-carbohydrate interactions. Distortion of the ligand as a determinant of affinity.

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
C	SCOP2B Superfamily	Mannose-binding lectins	8086726	3001715	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	Mannose-binding lectins	8086726	3001715	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	Mannose-binding lectins	8086726	3001715	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	Mannose-binding lectins	8086726	3001715	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
C	Jacalin	e4r6qC1	A: beta duplicates or obligate multimers	X: beta-Prism I (From Topology)	H: beta-Prism I (From Topology)	T: beta-Prism I	F: Jacalin	ECOD (1.6)
E	Jacalin	e4r6qE1	A: beta duplicates or obligate multimers	X: beta-Prism I (From Topology)	H: beta-Prism I (From Topology)	T: beta-Prism I	F: Jacalin	ECOD (1.6)
A	Jacalin	e4r6qA1	A: beta duplicates or obligate multimers	X: beta-Prism I (From Topology)	H: beta-Prism I (From Topology)	T: beta-Prism I	F: Jacalin	ECOD (1.6)
G	Jacalin	e4r6qG1	A: beta duplicates or obligate multimers	X: beta-Prism I (From Topology)	H: beta-Prism I (From Topology)	T: beta-Prism I	F: Jacalin	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
C	2.100.10.30	Mainly Beta	Aligned Prism	Vitelline Membrane Outer Layer Protein I, subunit A	Jacalin-like lectin domain	CATH (4.3.0)
E	2.100.10.30	Mainly Beta	Aligned Prism	Vitelline Membrane Outer Layer Protein I, subunit A	Jacalin-like lectin domain	CATH (4.3.0)
A	2.100.10.30	Mainly Beta	Aligned Prism	Vitelline Membrane Outer Layer Protein I, subunit A	Jacalin-like lectin domain	CATH (4.3.0)
G	2.100.10.30	Mainly Beta	Aligned Prism	Vitelline Membrane Outer Layer Protein I, subunit A	Jacalin-like lectin domain	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, C, E, G	PF01419	Jacalin-like lectin domain (Jacalin)	Jacalin-like lectin domain	-	Repeat

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, C, E, G	Agglutinin alpha chain	binding carbohydrate binding protein-containing complex binding immunoglobulin binding IgA binding	-	-
B, D, F, H	Agglutinin beta-3 chain	binding carbohydrate binding protein-containing complex binding immunoglobulin binding IgA binding	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, C, E, G	IPR036404	Jacalin-like lectin domain superfamily	Homologous Superfamily
A, C, E, G	IPR033734	Jacalin-like lectin domain, plant	Domain
A, C, E, G	IPR001229	Jacalin-like lectin domain	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.