Annotations: 5AED

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Glyco_hydro_31_C	e5aedA2	A: beta sandwiches	X: Glycosyl hydrolase domain-like	H: Glycosyl hydrolase domain (From Topology)	T: Glycosyl hydrolase domain	F: Glyco_hydro_31_C	ECOD (1.6)
A	Gal_mutarotas_2	e5aedA3	A: beta sandwiches	X: Glycosyl hydrolase domain-like	H: supersandwich (From Topology)	T: supersandwich	F: Gal_mutarotas_2	ECOD (1.6)
A	Glyco_hydro_31_N	e5aedA1	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: Glyco_hydro_31_N	ECOD (1.6)
B	Glyco_hydro_31_C	e5aedB2	A: beta sandwiches	X: Glycosyl hydrolase domain-like	H: Glycosyl hydrolase domain (From Topology)	T: Glycosyl hydrolase domain	F: Glyco_hydro_31_C	ECOD (1.6)
B	Gal_mutarotas_2	e5aedB3	A: beta sandwiches	X: Glycosyl hydrolase domain-like	H: supersandwich (From Topology)	T: supersandwich	F: Gal_mutarotas_2	ECOD (1.6)
B	Glyco_hydro_31_N	e5aedB1	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: Glyco_hydro_31_N	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	2.60.40.1180	Mainly Beta	Sandwich	Immunoglobulin-like	Golgi alpha-mannosidase II	CATH (utative)
B	2.60.40.1180	Mainly Beta	Sandwich	Immunoglobulin-like	Golgi alpha-mannosidase II	CATH (utative)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF21365	Glycosyl hydrolase family 31 C-terminal domain (Glyco_hydro_31_3rd)	Glycosyl hydrolase family 31 C-terminal domain	Glycosyl hydrolases are key enzymes of carbohydrate metabolism. Family 31 comprises of enzymes that are, or similar to, alpha- galactosidases. This entry represents the 3rd beta sandwich domain.	Domain
A, B	PF13802	Glycosyl hydrolase 31 N-terminal galactose mutarotase-like domain (Gal_mutarotas_2)	Glycosyl hydrolase 31 N-terminal galactose mutarotase-like domain	This entry represents the first of three common domains found in Glycosyl hydrolase 31 family proteins. It has a galactose mutarotase superfamily fold.	Domain
A, B	PF01055	Glycosyl hydrolases family 31 TIM-barrel domain (Glyco_hydro_31_2nd)	Glycosyl hydrolases family 31 TIM-barrel domain	Glycosyl hydrolases are key enzymes of carbohydrate metabolism. Family 31 comprises of enzymes that are, or similar to, alpha- galactosidases. This entry corresponds to the second domain of family 31 enzymes and adopts a TIM-barrel fold.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	ALPHA-GLUCOSIDASE YIHQ	binding carbohydrate binding hydrolase activity, acting on glycosyl bonds hydrolase activity sulfoquinovosidase activity catalytic activity hydrolase activity, hydrolyzing O-glycosyl compounds	carbohydrate metabolic process primary metabolic process metabolic process cellular process catabolic process ketone metabolic process organic hydroxy compound metabolic process carbohydrate derivative metabolic process alcohol metabolic process organic acid metabolic process 6-sulfoquinovose(1-) catabolic process organic acid catabolic process cellular catabolic process phosphate-containing compound metabolic process carbohydrate metabolic process primary metabolic process metabolic process cellular process catabolic process ketone metabolic process organic hydroxy compound metabolic process carbohydrate derivative metabolic process alcohol metabolic process organic acid metabolic process 6-sulfoquinovose(1-) catabolic process organic acid catabolic process cellular catabolic process phosphate-containing compound metabolic process small molecule metabolic process sulfur compound metabolic process phosphorus metabolic process 6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde carbohydrate derivative catabolic process aldehyde metabolic process sulfur compound catabolic process secondary alcohol metabolic process 6-sulfoquinovose(1-) metabolic process organophosphate metabolic process small molecule catabolic process alkanesulfonate metabolic process primary alcohol metabolic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR000322	Glycoside hydrolase family 31, TIM barrel domain	Domain
A, B	IPR048395	Glycosyl hydrolase family 31, C-terminal domain	Domain
A, B	IPR017853	Glycoside hydrolase superfamily	Homologous Superfamily
A, B	IPR044112	Sulfoquinovosidase YihQ-like, TIM barrel domain	Domain
A, B	IPR013780	Glycosyl hydrolase, all-beta	Homologous Superfamily
A, B	IPR025887	Glycoside hydrolase family 31, N-terminal domain	Domain
A, B	IPR011013	Galactose mutarotase-like domain superfamily	Homologous Superfamily
A, B	IPR052990	Sulfoquinovosidase Glycosyl Hydrolase	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.