Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AFAD-oxidase_Ce5fxfA2 A: a+b two layersX: Alpha-beta plaitsH: FAD-linked oxidases, C-terminal domain (From Topology)T: FAD-linked oxidases, C-terminal domainF: FAD-oxidase_CECOD (1.6)
AFAD_binding_4e5fxfA1 A: a+b complex topologyX: FAD-binding domain-likeH: FAD-binding domain (From Topology)T: FAD-binding domainF: FAD_binding_4ECOD (1.6)
BFAD-oxidase_Ce5fxfB2 A: a+b two layersX: Alpha-beta plaitsH: FAD-linked oxidases, C-terminal domain (From Topology)T: FAD-linked oxidases, C-terminal domainF: FAD-oxidase_CECOD (1.6)
BFAD_binding_4e5fxfB1 A: a+b complex topologyX: FAD-binding domain-likeH: FAD-binding domain (From Topology)T: FAD-binding domainF: FAD_binding_4ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B
PF02913FAD linked oxidases, C-terminal domain (FAD-oxidase_C)FAD linked oxidases, C-terminal domainThis domain has a ferredoxin-like fold.Domain
A, B
PF01565FAD binding domain (FAD_binding_4)FAD binding domainThis family consists of various enzymes that use FAD as a co-factor, most of the enzymes are similar to oxygen oxidoreductase. One of the enzymes Vanillyl-alcohol oxidase (VAO) has a solved structure, the alignment includes the FAD binding site, call ...This family consists of various enzymes that use FAD as a co-factor, most of the enzymes are similar to oxygen oxidoreductase. One of the enzymes Vanillyl-alcohol oxidase (VAO) has a solved structure, the alignment includes the FAD binding site, called the PP-loop, between residues 99-110 [1]. The FAD molecule is covalently bound in the known structure, however the residue that links to the FAD is not in the alignment. VAO catalyses the oxidation of a wide variety of substrates, ranging form aromatic amines to 4-alkylphenols. Other members of this family include D-lactate dehydrogenase, this enzyme catalyses the conversion of D-lactate to pyruvate using FAD as a co-factor; mitomycin radical oxidase, this enzyme oxidises the reduced form of mitomycins and is involved in mitomycin resistance. This family includes MurB an UDP-N-acetylenolpyruvoylglucosamine reductase enzyme EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan [2].
Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B
EUGENOL OXIDASE -