5I6Z
X-ray structure of the ts2 human serotonin transporter
External Resource: Annotation
- Domain Annotation: ECOD Classification
- IMGT Antibody Annotation
- SAbDab Antibody Annotation
- Protein Family Annotation
- Gene Ontology: Gene Product Annotation
- InterPro: Protein Family Classification
- Pharos: Disease Associations
- Membrane Protein Annotation: PDBTM
- Membrane Protein Annotation: MemProtMD
- Membrane Protein Annotation: mpstruc
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | SNF | e5i6zA1 | A: alpha complex topology | X: Sodium:neurotransmitter symporter family (SNF)-like (From Topology) | H: Sodium:neurotransmitter symporter family (SNF)-like (From Topology) | T: Sodium:neurotransmitter symporter family (SNF)-like | F: SNF | ECOD (1.6) |
C | C1-set_4 | e5i6zC1 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: C1-set_4 | ECOD (1.6) |
C | V-set | e5i6zC2 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: V-set | ECOD (1.6) |
B | V-set_8 | e5i6zB2 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: V-set_8 | ECOD (1.6) |
B | C1-set_1 | e5i6zB1 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: C1-set_1 | ECOD (1.6) |
IMGT Antibody Annotation IMGT Database Homepage
Chain | Protein Name | Description | Organism Name | Gene Allele Name(s) | Domain Name(s) | Receptor Type | Receptor Description | Provenance Source |
---|---|---|---|---|---|---|---|---|
8B6 Fab | L-KAPPA | Mus musculus (house mouse) | IGKV6-17*01, IGKJ1*01, IGKJ2*01, IGKC*01, IGKC*02 | V-DOMAIN V-KAPPA, C-DOMAIN C-KAPPA | IG | FAB-GAMMA-2B_KAPPA | IMGT (202445-0) | |
8B6 Fab | VH-CH1 | Mus musculus (house mouse) | IGHV1-26*01, IGHJ2*01, IGHG2B*02 | V-DOMAIN VH, C-DOMAIN CH1 | IG | FAB-GAMMA-2B_KAPPA | IMGT (202445-0) |
SAbDab Antibody Annotation SAbDab Database Homepage
Chain | Chain Class | Chain Subclass | Chain Type | Antigen Name(s) | Provenance Source |
---|---|---|---|---|---|
Light Chain | IGKV6 | Kappa | sodium-dependent serotonin transporter | SAbDab (2024-11-15) | |
Heavy Chain | IGHV1 | - | sodium-dependent serotonin transporter | SAbDab (2024-11-15) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF00209 | Sodium:neurotransmitter symporter family (SNF) | Sodium:neurotransmitter symporter family | - | Family | |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR000175 | Sodium:neurotransmitter symporter | Family | |
IPR037272 | Sodium:neurotransmitter symporter superfamily | Homologous Superfamily | |
IPR013086 | Sodium:neurotransmitter symporter, serotonin, N-terminal | Domain |
Pharos: Disease Associations Pharos Homepage Annotation
Membrane Protein Annotation: PDBTM PDBTM Database Homepage
Chains | External Link | Comment |
---|---|---|
PDBTM | Annotated as membrane protein by PDBTM |
Membrane Protein Annotation: MemProtMD MemProtMD Database Homepage
Chains | External Link | Comment |
---|---|---|
MemProtMD | Annotated as membrane protein by MemProtMD |