5JBF

4,6-alpha-glucanotransferase GTFB (D1015N mutant) from Lactobacillus reuteri 121 complexed with maltopentaose

External Resource: Annotation

Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Glyco_hydro_70_2nd	e5jbfA1	A: beta sandwiches	X: Glycosyl hydrolase domain-like	H: Glycosyl hydrolase domain (From Topology)	T: Glycosyl hydrolase domain	F: Glyco_hydro_70_2nd	ECOD (1.6)
A	Glyco_hydro_70_1st	e5jbfA3	A: alpha bundles	X: Helical domain in glucansucrase GTF180 (From Topology)	H: Helical domain in glucansucrase GTF180 (From Topology)	T: Helical domain in glucansucrase GTF180	F: Glyco_hydro_70_1st	ECOD (1.6)
A	Alpha-amylase	e5jbfA2	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: Alpha-amylase	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.20.20.80	Alpha Beta	Alpha-Beta Barrel	TIM Barrel	Glycosidases	CATH (4.3.0)
A	3.20.20.470	Alpha Beta	Alpha-Beta Barrel	TIM Barrel	Glucansucrase	CATH (4.3.0)
B	3.20.20.80	Alpha Beta	Alpha-Beta Barrel	TIM Barrel	Glycosidases	CATH (4.3.0)
B	3.20.20.470	Alpha Beta	Alpha-Beta Barrel	TIM Barrel	Glucansucrase	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF02324	Glycosyl hydrolase family 70 (Glyco_hydro_70)	Glycosyl hydrolase family 70	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Inactive glucansucrase	dextransucrase activity glycosyltransferase activity transferase activity hexosyltransferase activity catalytic activity glucosyltransferase activity hydrolase activity, acting on glycosyl bonds amylase activity alpha-amylase activity hydrolase activity, hydrolyzing O-glycosyl compounds hydrolase activity cation binding ion binding binding dextransucrase activity glycosyltransferase activity transferase activity hexosyltransferase activity catalytic activity glucosyltransferase activity hydrolase activity, acting on glycosyl bonds amylase activity alpha-amylase activity hydrolase activity, hydrolyzing O-glycosyl compounds hydrolase activity cation binding ion binding binding metal ion binding small molecule binding	carbohydrate metabolic process glucan biosynthetic process polysaccharide biosynthetic process cellular biosynthetic process carbohydrate biosynthetic process cellular metabolic process primary metabolic process macromolecule biosynthetic process polysaccharide metabolic process glucan metabolic process biosynthetic process metabolic process cellular process macromolecule metabolic process	extracellular region extracellular space cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR022263	KxYKxGKxW signal peptide	Conserved Site
A, B	IPR017853	Glycoside hydrolase superfamily	Homologous Superfamily
A, B	IPR003318	Glycoside hydrolase, family 70, catalytic domain	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.