5KY0
mouse POFUT1 in complex with mouse Notch1 EGF12(D464G) and GDP
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
B | d5ky0b_ | Small proteins | Knottins (small inhibitors, toxins, lectins) | EGF/Laminin | automated matches | automated matches | Mouse (Mus musculus ) [TaxId: 10090 ], | SCOPe (2.08) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | O-FucT_C | e5ky0A2 | A: a/b three-layered sandwiches | X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology) | H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology) | T: UDP-Glycosyltransferase/glycogen phosphorylase | F: O-FucT_C | ECOD (1.6) |
A | O-FucT_N | e5ky0A1 | A: a/b three-layered sandwiches | X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology) | H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology) | T: UDP-Glycosyltransferase/glycogen phosphorylase | F: O-FucT_N | ECOD (1.6) |
B | hEGF_2 | e5ky0B1 | A: few secondary structure elements | X: EGF-like | H: EGF-related | T: EGF/Laminin | F: hEGF_2 | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A | 3.40.50.11340 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | CATH (4.3.0) | |
A | 3.40.50.11350 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF10250 | GDP-fucose protein O-fucosyltransferase (O-FucT) | GDP-fucose protein O-fucosyltransferase | - | Family | |
PF12661 | Human growth factor-like EGF (hEGF) | Human growth factor-like EGF | hEGF, or human growth factor-like EGF, domains have six conserved residues disulfide-bonded into the characteristic 'ababcc' pattern. They are involved in growth and proliferation of cells, in proteins of the Notch/Delta pathway, neurogulin and selec ... | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR039922 | GDP-fucose protein O-fucosyltransferase 1 | Family | |
IPR019378 | GDP-fucose protein O-fucosyltransferase | Family | |
IPR013032 | EGF-like, conserved site | Conserved Site | |
IPR022362 | Neurogenic locus notch homolog protein 1 | Family | |
IPR036770 | Ankyrin repeat-containing domain superfamily | Homologous Superfamily | |
IPR000742 | EGF-like domain | Domain | |
IPR035993 | Notch-like domain superfamily | Homologous Superfamily | |
IPR011656 | Notch, NODP domain | Domain | |
IPR010660 | Notch, NOD domain | Domain | |
IPR008297 | Notch | Family | |
IPR000800 | Notch domain | Domain | |
IPR000152 | EGF-type aspartate/asparagine hydroxylation site | PTM | |
IPR001881 | EGF-like calcium-binding domain | Domain | |
IPR009030 | Growth factor receptor cysteine-rich domain superfamily | Homologous Superfamily | |
IPR018097 | EGF-like calcium-binding, conserved site | Conserved Site | |
IPR002110 | Ankyrin repeat | Repeat | |
IPR049883 | NOTCH1 EGF-like calcium-binding domain | Domain | |
IPR051022 | Notch Signaling and Cell Fate Determination | Family | |
IPR024600 | Notch, C-terminal | Domain |