Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AGSH_synth_ATPe5oesA2 A: a+b complex topologyX: Protein kinase/SAICAR synthase/ATP-grasp (From Homology)H: Protein kinase/SAICAR synthase/ATP-graspT: ATP-graspF: GSH_synth_ATPECOD (1.6)
AGSH_synthasee5oesA1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: PreATP-grasp domainF: GSH_synthaseECOD (1.6)
BGSH_synth_ATPe5oesB2 A: a+b complex topologyX: Protein kinase/SAICAR synthase/ATP-grasp (From Homology)H: Protein kinase/SAICAR synthase/ATP-graspT: ATP-graspF: GSH_synth_ATPECOD (1.6)
BGSH_synthasee5oesB1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: PreATP-grasp domainF: GSH_synthaseECOD (1.6)
CGSH_synth_ATPe5oesC1 A: a+b complex topologyX: Protein kinase/SAICAR synthase/ATP-grasp (From Homology)H: Protein kinase/SAICAR synthase/ATP-graspT: ATP-graspF: GSH_synth_ATPECOD (1.6)
CGSH_synthasee5oesC2 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: PreATP-grasp domainF: GSH_synthaseECOD (1.6)
DGSH_synth_ATPe5oesD2 A: a+b complex topologyX: Protein kinase/SAICAR synthase/ATP-grasp (From Homology)H: Protein kinase/SAICAR synthase/ATP-graspT: ATP-graspF: GSH_synth_ATPECOD (1.6)
DGSH_synthasee5oesD1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: PreATP-grasp domainF: GSH_synthaseECOD (1.6)
EGSH_synth_ATPe5oesE1 A: a+b complex topologyX: Protein kinase/SAICAR synthase/ATP-grasp (From Homology)H: Protein kinase/SAICAR synthase/ATP-graspT: ATP-graspF: GSH_synth_ATPECOD (1.6)
EGSH_synthasee5oesE2 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: PreATP-grasp domainF: GSH_synthaseECOD (1.6)
FGSH_synth_ATPe5oesF1 A: a+b complex topologyX: Protein kinase/SAICAR synthase/ATP-grasp (From Homology)H: Protein kinase/SAICAR synthase/ATP-graspT: ATP-graspF: GSH_synth_ATPECOD (1.6)
FGSH_synthasee5oesF2 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: PreATP-grasp domainF: GSH_synthaseECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A3.30.1490.80 Alpha Beta 2-Layer Sandwich Dna Ligase domain 1CATH (4.3.0)
A3.30.470.20 Alpha Beta 2-Layer Sandwich D-amino Acid Aminotransferase Chain A, domain 1CATH (4.3.0)
A1.10.1080.10 Mainly Alpha Orthogonal Bundle Glutathione Synthetase Chain A, domain 3CATH (4.3.0)
A3.40.50.1760 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold Glutathione synthase, substrate-binding domain superfamily, eukaryoticCATH (4.3.0)
B3.30.1490.80 Alpha Beta 2-Layer Sandwich Dna Ligase domain 1CATH (4.3.0)
B3.30.470.20 Alpha Beta 2-Layer Sandwich D-amino Acid Aminotransferase Chain A, domain 1CATH (4.3.0)
B1.10.1080.10 Mainly Alpha Orthogonal Bundle Glutathione Synthetase Chain A, domain 3CATH (4.3.0)
B3.40.50.1760 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold Glutathione synthase, substrate-binding domain superfamily, eukaryoticCATH (4.3.0)
C3.30.1490.80 Alpha Beta 2-Layer Sandwich Dna Ligase domain 1CATH (4.3.0)
C3.30.470.20 Alpha Beta 2-Layer Sandwich D-amino Acid Aminotransferase Chain A, domain 1CATH (4.3.0)
C1.10.1080.10 Mainly Alpha Orthogonal Bundle Glutathione Synthetase Chain A, domain 3CATH (4.3.0)
C3.40.50.1760 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold Glutathione synthase, substrate-binding domain superfamily, eukaryoticCATH (4.3.0)
D3.30.1490.80 Alpha Beta 2-Layer Sandwich Dna Ligase domain 1CATH (4.3.0)
D3.30.470.20 Alpha Beta 2-Layer Sandwich D-amino Acid Aminotransferase Chain A, domain 1CATH (4.3.0)
D1.10.1080.10 Mainly Alpha Orthogonal Bundle Glutathione Synthetase Chain A, domain 3CATH (4.3.0)
D3.40.50.1760 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold Glutathione synthase, substrate-binding domain superfamily, eukaryoticCATH (4.3.0)
E3.30.1490.80 Alpha Beta 2-Layer Sandwich Dna Ligase domain 1CATH (4.3.0)
E3.30.470.20 Alpha Beta 2-Layer Sandwich D-amino Acid Aminotransferase Chain A, domain 1CATH (4.3.0)
E1.10.1080.10 Mainly Alpha Orthogonal Bundle Glutathione Synthetase Chain A, domain 3CATH (4.3.0)
E3.40.50.1760 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold Glutathione synthase, substrate-binding domain superfamily, eukaryoticCATH (4.3.0)
F3.30.1490.80 Alpha Beta 2-Layer Sandwich Dna Ligase domain 1CATH (4.3.0)
F3.30.470.20 Alpha Beta 2-Layer Sandwich D-amino Acid Aminotransferase Chain A, domain 1CATH (4.3.0)
F1.10.1080.10 Mainly Alpha Orthogonal Bundle Glutathione Synthetase Chain A, domain 3CATH (4.3.0)
F3.40.50.1760 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold Glutathione synthase, substrate-binding domain superfamily, eukaryoticCATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B, C, D, E
PF03917Eukaryotic glutathione synthase, ATP binding domain (GSH_synth_ATP)Eukaryotic glutathione synthase, ATP binding domain- Domain
A, B, C, D, E
PF03199Eukaryotic glutathione synthase (GSH_synthase)Eukaryotic glutathione synthase- Domain

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
A, B, C, D, E
IPR014709Glutathione synthase, C-terminal, eukaryoticHomologous Superfamily
A, B, C, D, E
IPR016185Pre-ATP-grasp domain superfamilyHomologous Superfamily
A, B, C, D, E
IPR014042Glutathione synthase, alpha-helicalHomologous Superfamily
A, B, C, D, E
IPR037013Glutathione synthase, substrate-binding domain superfamilyHomologous Superfamily
A, B, C, D, E
IPR014049Glutathione synthase, N-terminal, eukaryoticHomologous Superfamily
A, B, C, D, E
IPR005615Glutathione synthaseFamily
A, B, C, D, E
IPR004887Glutathione synthase, substrate-binding domainDomain