Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B SuperfamilyeIF4e-like 8072936 3001871 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyeIF4e-like 8072936 3001871 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AIF4Ee5t47A1 A: a+b two layersX: Translation initiation factor eIF4e and phosphothreonine lyase (From Topology)H: Translation initiation factor eIF4e and phosphothreonine lyase (From Topology)T: Translation initiation factor eIF4e and phosphothreonine lyaseF: IF4EECOD (1.6)
CIF4Ee5t47C1 A: a+b two layersX: Translation initiation factor eIF4e and phosphothreonine lyase (From Topology)H: Translation initiation factor eIF4e and phosphothreonine lyase (From Topology)T: Translation initiation factor eIF4e and phosphothreonine lyaseF: IF4EECOD (1.6)
BeIF_4G1_likee5t47B1 A: alpha arraysX: Eukaryotic initiation factor 4f subunit eIF4g, eIF4e-binding domain (From Topology)H: Eukaryotic initiation factor 4f subunit eIF4g, eIF4e-binding domain (From Topology)T: Eukaryotic initiation factor 4f subunit eIF4g, eIF4e-binding domainF: eIF_4G1_likeECOD (1.6)
DeIF_4G1_likee5t47D1 A: alpha arraysX: Eukaryotic initiation factor 4f subunit eIF4g, eIF4e-binding domain (From Topology)H: Eukaryotic initiation factor 4f subunit eIF4g, eIF4e-binding domain (From Topology)T: Eukaryotic initiation factor 4f subunit eIF4g, eIF4e-binding domainF: eIF_4G1_likeECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, C
PF01652Eukaryotic initiation factor 4E (IF4E)Eukaryotic initiation factor 4E- Domain
B, D
PF21140Translation initiation factor eIF4G-like, eIF4E-binding domain (eIF4G1-like_eIF4E-bd)Translation initiation factor eIF4G-like, eIF4E-binding domainThis domain is found in proteins from animals, including Translation initiation factor eIF4G (eIF4G1) from Drosophila melanogaster. This domain shows a canonical helix, a linker and an elbow loop. It shows a conserved sequence YXR/KXXLXXXR/K/Q that p ...This domain is found in proteins from animals, including Translation initiation factor eIF4G (eIF4G1) from Drosophila melanogaster. This domain shows a canonical helix, a linker and an elbow loop. It shows a conserved sequence YXR/KXXLXXXR/K/Q that plays a role in the interaction with eIF4E [1,2].
Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, C
Eukaryotic translation initiation factor 4E
B, D
Eukaryotic translation initiation factor 4G, isoform A