5UQH

Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Campylobacter jejuni in the complex with inhibitor p182

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d5uqha1	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	Inosine monophosphate dehydrogenase (IMPDH)	automated matches	automated matches	(Campylobacter jejuni subsp. jejuni ) [TaxId: 32022 ], (Campylobacter jejuni subsp. jejuni CG8486 ) [TaxId: 398000 ],	SCOPe (2.08)
A	d5uqha2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Campylobacter jejuni subsp. jejuni ) [TaxId: 32022 ], (Campylobacter jejuni subsp. jejuni CG8486 ) [TaxId: 398000 ],	SCOPe (2.08)
B	d5uqhb1	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	Inosine monophosphate dehydrogenase (IMPDH)	automated matches	automated matches	(Campylobacter jejuni subsp. jejuni ) [TaxId: 32022 ], (Campylobacter jejuni subsp. jejuni CG8486 ) [TaxId: 398000 ],	SCOPe (2.08)
B	d5uqhb2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Campylobacter jejuni subsp. jejuni ) [TaxId: 32022 ], (Campylobacter jejuni subsp. jejuni CG8486 ) [TaxId: 398000 ],	SCOPe (2.08)
C	d5uqhc1	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	Inosine monophosphate dehydrogenase (IMPDH)	automated matches	automated matches	(Campylobacter jejuni subsp. jejuni ) [TaxId: 32022 ], (Campylobacter jejuni subsp. jejuni CG8486 ) [TaxId: 398000 ],	SCOPe (2.08)
C	d5uqhc2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Campylobacter jejuni subsp. jejuni ) [TaxId: 32022 ], (Campylobacter jejuni subsp. jejuni CG8486 ) [TaxId: 398000 ],	SCOPe (2.08)
D	d5uqhd1	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	Inosine monophosphate dehydrogenase (IMPDH)	automated matches	automated matches	(Campylobacter jejuni subsp. jejuni ) [TaxId: 32022 ], (Campylobacter jejuni subsp. jejuni CG8486 ) [TaxId: 398000 ],	SCOPe (2.08)
D	d5uqhd2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Campylobacter jejuni subsp. jejuni ) [TaxId: 32022 ], (Campylobacter jejuni subsp. jejuni CG8486 ) [TaxId: 398000 ],	SCOPe (2.08)
E	d5uqhe1	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	Inosine monophosphate dehydrogenase (IMPDH)	automated matches	automated matches	(Campylobacter jejuni subsp. jejuni ) [TaxId: 32022 ], (Campylobacter jejuni subsp. jejuni CG8486 ) [TaxId: 398000 ],	SCOPe (2.08)
E	d5uqhe2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Campylobacter jejuni subsp. jejuni ) [TaxId: 32022 ], (Campylobacter jejuni subsp. jejuni CG8486 ) [TaxId: 398000 ],	SCOPe (2.08)
F	d5uqhf1	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	Inosine monophosphate dehydrogenase (IMPDH)	automated matches	automated matches	(Campylobacter jejuni subsp. jejuni ) [TaxId: 32022 ], (Campylobacter jejuni subsp. jejuni CG8486 ) [TaxId: 398000 ],	SCOPe (2.08)
F	d5uqhf2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Campylobacter jejuni subsp. jejuni ) [TaxId: 32022 ], (Campylobacter jejuni subsp. jejuni CG8486 ) [TaxId: 398000 ],	SCOPe (2.08)
G	d5uqhg1	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	Inosine monophosphate dehydrogenase (IMPDH)	automated matches	automated matches	(Campylobacter jejuni subsp. jejuni ) [TaxId: 32022 ], (Campylobacter jejuni subsp. jejuni CG8486 ) [TaxId: 398000 ],	SCOPe (2.08)
G	d5uqhg2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Campylobacter jejuni subsp. jejuni ) [TaxId: 32022 ], (Campylobacter jejuni subsp. jejuni CG8486 ) [TaxId: 398000 ],	SCOPe (2.08)
H	d5uqhh1	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	Inosine monophosphate dehydrogenase (IMPDH)	automated matches	automated matches	(Campylobacter jejuni subsp. jejuni ) [TaxId: 32022 ], (Campylobacter jejuni subsp. jejuni CG8486 ) [TaxId: 398000 ],	SCOPe (2.08)
H	d5uqhh2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Campylobacter jejuni subsp. jejuni ) [TaxId: 32022 ], (Campylobacter jejuni subsp. jejuni CG8486 ) [TaxId: 398000 ],	SCOPe (2.08)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	IMPDH_1st	e5uqhA1	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: IMPDH_1st	ECOD (1.6)
B	IMPDH_1st	e5uqhB1	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: IMPDH_1st	ECOD (1.6)
C	IMPDH_1st	e5uqhC1	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: IMPDH_1st	ECOD (1.6)
D	IMPDH_1st	e5uqhD1	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: IMPDH_1st	ECOD (1.6)
E	IMPDH_1st	e5uqhE1	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: IMPDH_1st	ECOD (1.6)
F	IMPDH_1st	e5uqhF1	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: IMPDH_1st	ECOD (1.6)
G	IMPDH_1st	e5uqhG1	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: IMPDH_1st	ECOD (1.6)
H	IMPDH_1st	e5uqhH1	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: IMPDH_1st	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.20.20.70	Alpha Beta	Alpha-Beta Barrel	TIM Barrel	Aldolase class I	CATH (4.3.0)
B	3.20.20.70	Alpha Beta	Alpha-Beta Barrel	TIM Barrel	Aldolase class I	CATH (4.3.0)
C	3.20.20.70	Alpha Beta	Alpha-Beta Barrel	TIM Barrel	Aldolase class I	CATH (4.3.0)
D	3.20.20.70	Alpha Beta	Alpha-Beta Barrel	TIM Barrel	Aldolase class I	CATH (4.3.0)
E	3.20.20.70	Alpha Beta	Alpha-Beta Barrel	TIM Barrel	Aldolase class I	CATH (4.3.0)
F	3.20.20.70	Alpha Beta	Alpha-Beta Barrel	TIM Barrel	Aldolase class I	CATH (4.3.0)
G	3.20.20.70	Alpha Beta	Alpha-Beta Barrel	TIM Barrel	Aldolase class I	CATH (4.3.0)
H	3.20.20.70	Alpha Beta	Alpha-Beta Barrel	TIM Barrel	Aldolase class I	CATH (4.3.0)

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.