Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B SuperfamilyL domain-like 8038760 3001010 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyGrowth factor receptor domain-like 8038763 3000398 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyGrowth factor receptor domain-like 8038763 3000398 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyL domain-like 8038760 3001010 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyL domain-like 8038760 3001010 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyGrowth factor receptor domain-like 8038763 3000398 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyL domain-like 8038760 3001010 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyGrowth factor receptor domain-like 8038763 3000398 SCOP2B (2022-06-29)
ESCOP2B SuperfamilyEGF/Laminin-like 8036173 3000412 SCOP2B (2022-06-29)
FSCOP2B SuperfamilyEGF/Laminin-like 8036173 3000412 SCOP2B (2022-06-29)
GSCOP2B SuperfamilyEGF/Laminin-like 8036173 3000412 SCOP2B (2022-06-29)
HSCOP2B SuperfamilyEGF/Laminin-like 8036173 3000412 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
ARecep_L_domaine5wb7A1 A: beta duplicates or obligate multimersX: Single-stranded right-handed beta-helixH: Leucine-rich repeats (From Topology)T: Leucine-rich repeatsF: Recep_L_domainECOD (1.6)
AGF_recep_IV,Recep_L_domaine5wb7A2 A: beta duplicates or obligate multimersX: Single-stranded right-handed beta-helixH: Leucine-rich repeats (From Topology)T: Leucine-rich repeatsF: GF_recep_IV,Recep_L_domainECOD (1.6)
AFurin-likee5wb7A3 A: few secondary structure elementsX: EGF-likeH: Growth factor receptor domain (From Topology)T: Growth factor receptor domainF: Furin-likeECOD (1.6)
BRecep_L_domaine5wb7B1 A: beta duplicates or obligate multimersX: Single-stranded right-handed beta-helixH: Leucine-rich repeats (From Topology)T: Leucine-rich repeatsF: Recep_L_domainECOD (1.6)
BGF_recep_IV,Recep_L_domaine5wb7B3 A: beta duplicates or obligate multimersX: Single-stranded right-handed beta-helixH: Leucine-rich repeats (From Topology)T: Leucine-rich repeatsF: GF_recep_IV,Recep_L_domainECOD (1.6)
BFurin-likee5wb7B2 A: few secondary structure elementsX: EGF-likeH: Growth factor receptor domain (From Topology)T: Growth factor receptor domainF: Furin-likeECOD (1.6)
CRecep_L_domaine5wb7C1 A: beta duplicates or obligate multimersX: Single-stranded right-handed beta-helixH: Leucine-rich repeats (From Topology)T: Leucine-rich repeatsF: Recep_L_domainECOD (1.6)
CGF_recep_IV,Recep_L_domaine5wb7C2 A: beta duplicates or obligate multimersX: Single-stranded right-handed beta-helixH: Leucine-rich repeats (From Topology)T: Leucine-rich repeatsF: GF_recep_IV,Recep_L_domainECOD (1.6)
CFurin-likee5wb7C3 A: few secondary structure elementsX: EGF-likeH: Growth factor receptor domain (From Topology)T: Growth factor receptor domainF: Furin-likeECOD (1.6)
DRecep_L_domaine5wb7D3 A: beta duplicates or obligate multimersX: Single-stranded right-handed beta-helixH: Leucine-rich repeats (From Topology)T: Leucine-rich repeatsF: Recep_L_domainECOD (1.6)
DGF_recep_IV,Recep_L_domaine5wb7D1 A: beta duplicates or obligate multimersX: Single-stranded right-handed beta-helixH: Leucine-rich repeats (From Topology)T: Leucine-rich repeatsF: GF_recep_IV,Recep_L_domainECOD (1.6)
DFurin-likee5wb7D2 A: few secondary structure elementsX: EGF-likeH: Growth factor receptor domain (From Topology)T: Growth factor receptor domainF: Furin-likeECOD (1.6)
EEGF_1e5wb7E1 A: few secondary structure elementsX: EGF-likeH: EGF-relatedT: EGF/LamininF: EGF_1ECOD (1.6)
FEGF_1e5wb7F1 A: few secondary structure elementsX: EGF-likeH: EGF-relatedT: EGF/LamininF: EGF_1ECOD (1.6)
GEGF_1e5wb7G1 A: few secondary structure elementsX: EGF-likeH: EGF-relatedT: EGF/LamininF: EGF_1ECOD (1.6)
HEGF_1e5wb7H1 A: few secondary structure elementsX: EGF-likeH: EGF-relatedT: EGF/LamininF: EGF_1ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
E2.10.25.10 Mainly Beta Ribbon Laminin LamininCATH (4.3.0)
F2.10.25.10 Mainly Beta Ribbon Laminin LamininCATH (4.3.0)
G2.10.25.10 Mainly Beta Ribbon Laminin LamininCATH (4.3.0)
H2.10.25.10 Mainly Beta Ribbon Laminin LamininCATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B, C, D
PF00757Furin-like cysteine rich region (Furin-like)Furin-like cysteine rich region- Domain
A, B, C, D
PF01030Receptor L domain (Recep_L_domain)Receptor L domain- Repeat

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B, C, D
Epidermal growth factor receptor
E, F, G, H
Proepiregulin

Pharos: Disease Associations Pharos Homepage Annotation

ChainsDrug Target  Associated Disease
A, B, C, D
PharosP00533
E, F, G, H
PharosO14944