6CRD

INFLUENZA VIRUS NEURAMINIDASE SUBTYPE N9 (TERN) with tetrabrachion (TB) domain stalk

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Sialidases	8032977	3001607	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	Tetrabrachion	8039565	3001596	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Sialidases	8032977	3001607	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Tetrabrachion	8039565	3001596	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Sialidases	8032977	3001607	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Tetrabrachion	8039565	3001596	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	Tetrabrachion	8039565	3001596	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	Sialidases	8032977	3001607	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	Sialidases	8032977	3001607	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	Tetrabrachion	8039565	3001596	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	Tetrabrachion	8039565	3001596	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	Sialidases	8032977	3001607	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	Tetrabrachion	8039565	3001596	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	Sialidases	8032977	3001607	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	Sialidases	8032977	3001607	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	Tetrabrachion	8039565	3001596	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Neur	e6crdA1	A: beta duplicates or obligate multimers	X: beta-propeller-like	H: beta-propeller	T: 6-bladed	F: Neur	ECOD (1.6)
A	Tetrabrachion_like	e6crdA2	A: extended segments	X: AF1503 pre-HAMP domain (From Topology)	H: AF1503 pre-HAMP domain (From Topology)	T: AF1503 pre-HAMP domain	F: Tetrabrachion_like	ECOD (1.6)
B	Neur	e6crdB1	A: beta duplicates or obligate multimers	X: beta-propeller-like	H: beta-propeller	T: 6-bladed	F: Neur	ECOD (1.6)
B	Tetrabrachion_like	e6crdB2	A: extended segments	X: AF1503 pre-HAMP domain (From Topology)	H: AF1503 pre-HAMP domain (From Topology)	T: AF1503 pre-HAMP domain	F: Tetrabrachion_like	ECOD (1.6)
C	Neur	e6crdC1	A: beta duplicates or obligate multimers	X: beta-propeller-like	H: beta-propeller	T: 6-bladed	F: Neur	ECOD (1.6)
C	Tetrabrachion_like	e6crdC2	A: extended segments	X: AF1503 pre-HAMP domain (From Topology)	H: AF1503 pre-HAMP domain (From Topology)	T: AF1503 pre-HAMP domain	F: Tetrabrachion_like	ECOD (1.6)
D	Neur	e6crdD1	A: beta duplicates or obligate multimers	X: beta-propeller-like	H: beta-propeller	T: 6-bladed	F: Neur	ECOD (1.6)
D	Tetrabrachion_like	e6crdD2	A: extended segments	X: AF1503 pre-HAMP domain (From Topology)	H: AF1503 pre-HAMP domain (From Topology)	T: AF1503 pre-HAMP domain	F: Tetrabrachion_like	ECOD (1.6)
E	Neur	e6crdE1	A: beta duplicates or obligate multimers	X: beta-propeller-like	H: beta-propeller	T: 6-bladed	F: Neur	ECOD (1.6)
E	Tetrabrachion_like	e6crdE2	A: extended segments	X: AF1503 pre-HAMP domain (From Topology)	H: AF1503 pre-HAMP domain (From Topology)	T: AF1503 pre-HAMP domain	F: Tetrabrachion_like	ECOD (1.6)
F	Neur	e6crdF1	A: beta duplicates or obligate multimers	X: beta-propeller-like	H: beta-propeller	T: 6-bladed	F: Neur	ECOD (1.6)
F	Tetrabrachion_like	e6crdF2	A: extended segments	X: AF1503 pre-HAMP domain (From Topology)	H: AF1503 pre-HAMP domain (From Topology)	T: AF1503 pre-HAMP domain	F: Tetrabrachion_like	ECOD (1.6)
G	Neur	e6crdG1	A: beta duplicates or obligate multimers	X: beta-propeller-like	H: beta-propeller	T: 6-bladed	F: Neur	ECOD (1.6)
G	Tetrabrachion_like	e6crdG2	A: extended segments	X: AF1503 pre-HAMP domain (From Topology)	H: AF1503 pre-HAMP domain (From Topology)	T: AF1503 pre-HAMP domain	F: Tetrabrachion_like	ECOD (1.6)
H	Neur	e6crdH1	A: beta duplicates or obligate multimers	X: beta-propeller-like	H: beta-propeller	T: 6-bladed	F: Neur	ECOD (1.6)
H	Tetrabrachion_like	e6crdH2	A: extended segments	X: AF1503 pre-HAMP domain (From Topology)	H: AF1503 pre-HAMP domain (From Topology)	T: AF1503 pre-HAMP domain	F: Tetrabrachion_like	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	2.120.10.10	Mainly Beta	6 Propeller	Neuraminidase		CATH (utative)
B	2.120.10.10	Mainly Beta	6 Propeller	Neuraminidase		CATH (utative)
C	2.120.10.10	Mainly Beta	6 Propeller	Neuraminidase		CATH (utative)
D	2.120.10.10	Mainly Beta	6 Propeller	Neuraminidase		CATH (utative)
E	2.120.10.10	Mainly Beta	6 Propeller	Neuraminidase		CATH (utative)
F	2.120.10.10	Mainly Beta	6 Propeller	Neuraminidase		CATH (utative)
G	2.120.10.10	Mainly Beta	6 Propeller	Neuraminidase		CATH (utative)
H	2.120.10.10	Mainly Beta	6 Propeller	Neuraminidase		CATH (utative)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F, G, H	PF11401	Tetrabrachion (Tetrabrachion)	Tetrabrachion	-	Family
A, B, C, D, E A, B, C, D, E, F, G, H	PF00064	Neuraminidase (Neur)	Neuraminidase	-	Repeat

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F, G, H	Tetrabrachion,Neuraminidase	cation binding ion binding binding metal ion binding small molecule binding	carbohydrate metabolic process primary metabolic process metabolic process biological process involved in interspecies interaction between organisms non-lytic viral release viral budding viral life cycle biological process involved in interaction with host biological process involved in symbiotic interaction virion assembly exit from host cell viral process viral budding from plasma membrane viral release from host cell	membrane cellular anatomical entity host cell plasma membrane host cellular component host cell part host cell membrane virion component virion membrane

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F, G, H	IPR001860	Glycoside hydrolase, family 34	Family
A, B, C, D, E A, B, C, D, E, F, G, H	IPR033654	Sialidase, Influenza viruses A/B	Domain
A, B, C, D, E A, B, C, D, E, F, G, H	IPR036278	Sialidase superfamily	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F, G, H	IPR038065	Tetrabrachion, parallel right-handed coiled coil domain	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F, G, H	IPR021535	Tetrabrachion	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.