6CWJ

Crystal structures of cyanuric acid hydrolase from Moorella thermoacetica complexed with 1,3-Acetone Dicarboxylic Acid

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d6cwja1	Alpha and beta proteins (a+b)	Bacillus chorismate mutase-like	YjgF-like	Amidohydrolase ring-opening protein-like	automated matches	(Moorella thermoacetica ATCC 39073 ) [TaxId: 264732 ],	SCOPe (2.08)
A	d6cwja2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Moorella thermoacetica ATCC 39073 ) [TaxId: 264732 ],	SCOPe (2.08)
D	d6cwjd1	Alpha and beta proteins (a+b)	Bacillus chorismate mutase-like	YjgF-like	Amidohydrolase ring-opening protein-like	automated matches	(Moorella thermoacetica ATCC 39073 ) [TaxId: 264732 ],	SCOPe (2.08)
D	d6cwjd2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Moorella thermoacetica ATCC 39073 ) [TaxId: 264732 ],	SCOPe (2.08)
B	d6cwjb1	Alpha and beta proteins (a+b)	Bacillus chorismate mutase-like	YjgF-like	Amidohydrolase ring-opening protein-like	automated matches	(Moorella thermoacetica ATCC 39073 ) [TaxId: 264732 ],	SCOPe (2.08)
B	d6cwjb2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Moorella thermoacetica ATCC 39073 ) [TaxId: 264732 ],	SCOPe (2.08)
C	d6cwjc1	Alpha and beta proteins (a+b)	Bacillus chorismate mutase-like	YjgF-like	Amidohydrolase ring-opening protein-like	automated matches	(Moorella thermoacetica ATCC 39073 ) [TaxId: 264732 ],	SCOPe (2.08)
C	d6cwjc2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Moorella thermoacetica ATCC 39073 ) [TaxId: 264732 ],	SCOPe (2.08)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Amido_AtzD_TrzD_1st	e6cwjA2	A: a+b three layers	X: Bacillus chorismate mutase-like	H: YjgF-like (From Topology)	T: YjgF-like	F: Amido_AtzD_TrzD_1st	ECOD (1.6)
A	Amido_AtzD_TrzD_2nd	e6cwjA3	A: a+b three layers	X: Bacillus chorismate mutase-like	H: YjgF-like (From Topology)	T: YjgF-like	F: Amido_AtzD_TrzD_2nd	ECOD (1.6)
A	Amido_AtzD_TrzD_3rd	e6cwjA1	A: a+b three layers	X: Bacillus chorismate mutase-like	H: YjgF-like (From Topology)	T: YjgF-like	F: Amido_AtzD_TrzD_3rd	ECOD (1.6)
D	Amido_AtzD_TrzD_1st	e6cwjD2	A: a+b three layers	X: Bacillus chorismate mutase-like	H: YjgF-like (From Topology)	T: YjgF-like	F: Amido_AtzD_TrzD_1st	ECOD (1.6)
D	Amido_AtzD_TrzD_2nd	e6cwjD3	A: a+b three layers	X: Bacillus chorismate mutase-like	H: YjgF-like (From Topology)	T: YjgF-like	F: Amido_AtzD_TrzD_2nd	ECOD (1.6)
D	Amido_AtzD_TrzD_3rd	e6cwjD1	A: a+b three layers	X: Bacillus chorismate mutase-like	H: YjgF-like (From Topology)	T: YjgF-like	F: Amido_AtzD_TrzD_3rd	ECOD (1.6)
B	Amido_AtzD_TrzD_1st	e6cwjB1	A: a+b three layers	X: Bacillus chorismate mutase-like	H: YjgF-like (From Topology)	T: YjgF-like	F: Amido_AtzD_TrzD_1st	ECOD (1.6)
B	Amido_AtzD_TrzD_2nd	e6cwjB2	A: a+b three layers	X: Bacillus chorismate mutase-like	H: YjgF-like (From Topology)	T: YjgF-like	F: Amido_AtzD_TrzD_2nd	ECOD (1.6)
B	Amido_AtzD_TrzD_3rd	e6cwjB3	A: a+b three layers	X: Bacillus chorismate mutase-like	H: YjgF-like (From Topology)	T: YjgF-like	F: Amido_AtzD_TrzD_3rd	ECOD (1.6)
C	Amido_AtzD_TrzD_1st	e6cwjC3	A: a+b three layers	X: Bacillus chorismate mutase-like	H: YjgF-like (From Topology)	T: YjgF-like	F: Amido_AtzD_TrzD_1st	ECOD (1.6)
C	Amido_AtzD_TrzD_2nd	e6cwjC1	A: a+b three layers	X: Bacillus chorismate mutase-like	H: YjgF-like (From Topology)	T: YjgF-like	F: Amido_AtzD_TrzD_2nd	ECOD (1.6)
C	Amido_AtzD_TrzD_3rd	e6cwjC2	A: a+b three layers	X: Bacillus chorismate mutase-like	H: YjgF-like (From Topology)	T: YjgF-like	F: Amido_AtzD_TrzD_3rd	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.30.1330.170	Alpha Beta	2-Layer Sandwich	60s Ribosomal Protein L30	Chain: A	CATH (utative)
A	3.30.1330.160	Alpha Beta	2-Layer Sandwich	60s Ribosomal Protein L30	Chain: A	CATH (utative)
D	3.30.1330.170	Alpha Beta	2-Layer Sandwich	60s Ribosomal Protein L30	Chain: A	CATH (utative)
D	3.30.1330.160	Alpha Beta	2-Layer Sandwich	60s Ribosomal Protein L30	Chain: A	CATH (utative)
B	3.30.1330.170	Alpha Beta	2-Layer Sandwich	60s Ribosomal Protein L30	Chain: A	CATH (utative)
B	3.30.1330.160	Alpha Beta	2-Layer Sandwich	60s Ribosomal Protein L30	Chain: A	CATH (utative)
C	3.30.1330.170	Alpha Beta	2-Layer Sandwich	60s Ribosomal Protein L30	Chain: A	CATH (utative)
C	3.30.1330.160	Alpha Beta	2-Layer Sandwich	60s Ribosomal Protein L30	Chain: A	CATH (utative)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D	PF09663	Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) (Amido_AtzD_TrzD)	Amidohydrolase ring-opening protein (Amido_AtzD_TrzD)	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D	Cyanuric acid amidohydrolase	hydrolase activity cyanuric acid amidohydrolase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides catalytic activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds cation binding ion binding binding metal ion binding small molecule binding	cellular response to stimulus catabolic process response to stimulus response to xenobiotic stimulus cellular catabolic process s-triazine compound metabolic process polyamine catabolic process amine catabolic process atrazine metabolic process cellular response to xenobiotic stimulus cellular metabolic process cellular biogenic amine catabolic process polyamine metabolic process s-triazine compound catabolic process cellular response to stimulus catabolic process response to stimulus response to xenobiotic stimulus cellular catabolic process s-triazine compound metabolic process polyamine catabolic process amine catabolic process atrazine metabolic process cellular response to xenobiotic stimulus cellular metabolic process cellular biogenic amine catabolic process polyamine metabolic process s-triazine compound catabolic process xenobiotic catabolic process xenobiotic metabolic process amine metabolic process cellular response to chemical stimulus response to chemical atrazine catabolic process metabolic process cellular process biogenic amine metabolic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D	IPR043006	Cyanuric acid hydrolase/Barbiturase, repeating unit B	Homologous Superfamily
A, B, C, D	IPR043007	Cyanuric acid hydrolase/Barbiturase, repeating unit C	Homologous Superfamily
A, B, C, D	IPR014086	Cyanuric acid hydrolase/Barbiturase	Family
A, B, C, D	IPR043008	Cyanuric acid hydrolase/Barbiturase, repeating unit A	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.