Annotations: 6ESD

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A [auth B]	EUF08305	e6esdB1	A: a+b two layers	X: FAD-linked reductases, C-terminal domain-like	H: FAD-linked reductases-C (From Topology)	T: FAD-linked reductases-C	F: EUF08305	ECOD (1.6)
A [auth B]	Amino_oxidase_1st	e6esdB2	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: FAD/NAD(P)-binding domain	F: Amino_oxidase_1st	ECOD (1.6)
B [auth A]	EUF08305	e6esdA1	A: a+b two layers	X: FAD-linked reductases, C-terminal domain-like	H: FAD-linked reductases-C (From Topology)	T: FAD-linked reductases-C	F: EUF08305	ECOD (1.6)
B [auth A]	Amino_oxidase_1st	e6esdA2	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: FAD/NAD(P)-binding domain	F: Amino_oxidase_1st	ECOD (1.6)

Chains	Accession	Name	Description	Comments	Source
A [auth B], B [auth A]	PF01593	Flavin containing amine oxidoreductase (Amino_oxidase)	Flavin containing amine oxidoreductase	This family consists of various amine oxidases, including maze polyamine oxidase (PAO) [1] and various flavin containing monoamine oxidases (MAO). The aligned region includes the flavin binding site of these enzymes. The family also contains phytoene ...	This family consists of various amine oxidases, including maze polyamine oxidase (PAO) [1] and various flavin containing monoamine oxidases (MAO). The aligned region includes the flavin binding site of these enzymes. The family also contains phytoene dehydrogenases and related enzymes. In vertebrates MAO plays an important role regulating the intracellular levels of amines via there oxidation; these include various neurotransmitters, neurotoxins and trace amines [2]. In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium [3]. PAOs in plants, bacteria and protozoa oxidase spermidine and spermine to an aminobutyral, diaminopropane and hydrogen peroxide and are involved in the catabolism of polyamines [1]. Other members of this family include tryptophan 2-monooxygenase, putrescine oxidase, corticosteroid binding proteins and antibacterial glycoproteins.	Domain

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A [auth B], B [auth A]	Flavin-dependent L-tryptophan oxidase VioA	oxidoreductase activity catalytic activity cation binding ion binding binding metal ion binding small molecule binding	antibiotic metabolic process biosynthetic process metabolic process cellular process antibiotic biosynthetic process	-

Chains	Accession	Name	Type
A [auth B], B [auth A]	IPR002937	Amine oxidase	Domain
A [auth B], B [auth A]	IPR050464	Zeta Carotene Desaturase and Related Oxidoreductases	Family
A [auth B], B [auth A]	IPR036188	FAD/NAD(P)-binding domain superfamily	Homologous Superfamily