6GJQ
human NBD1 of CFTR in complex with nanobody T27
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
E | ABC_tran_1 | e6gjqE1 | A: a/b three-layered sandwiches | X: P-loop domains-like | H: P-loop domains-related | T: P-loop containing nucleoside triphosphate hydrolases | F: ABC_tran_1 | ECOD (1.6) |
G | ABC_tran_1 | e6gjqG1 | A: a/b three-layered sandwiches | X: P-loop domains-like | H: P-loop domains-related | T: P-loop containing nucleoside triphosphate hydrolases | F: ABC_tran_1 | ECOD (1.6) |
A | ABC_tran_1 | e6gjqA1 | A: a/b three-layered sandwiches | X: P-loop domains-like | H: P-loop domains-related | T: P-loop containing nucleoside triphosphate hydrolases | F: ABC_tran_1 | ECOD (1.6) |
C | ABC_tran_1 | e6gjqC1 | A: a/b three-layered sandwiches | X: P-loop domains-like | H: P-loop domains-related | T: P-loop containing nucleoside triphosphate hydrolases | F: ABC_tran_1 | ECOD (1.6) |
D | V-set_1 | e6gjqD1 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: V-set_1 | ECOD (1.6) |
F | V-set_1 | e6gjqF1 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: V-set_1 | ECOD (1.6) |
B | V-set_1 | e6gjqB1 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: V-set_1 | ECOD (1.6) |
H | V-set_1 | e6gjqH1 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: V-set_1 | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
E | 3.40.50.300 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | P-loop containing nucleotide triphosphate hydrolases | CATH (utative) |
G | 3.40.50.300 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | P-loop containing nucleotide triphosphate hydrolases | CATH (utative) |
A | 3.40.50.300 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | P-loop containing nucleotide triphosphate hydrolases | CATH (utative) |
C | 3.40.50.300 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | P-loop containing nucleotide triphosphate hydrolases | CATH (utative) |
SAbDab Antibody Annotation SAbDab Database Homepage
Chain | Chain Class | Chain Subclass | Chain Type | Antigen Name(s) | Provenance Source |
---|---|---|---|---|---|
Heavy Chain | IGHV1 | - | cystic fibrosis transmembrane conductance regulator | SAbDab (2024-11-01) |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR047082 | Cystic fibrosis transmembrane conductance regulator, ATP-binding cassette domain 1 | Domain | |
IPR003439 | ABC transporter-like, ATP-binding domain | Domain | |
IPR009147 | Cystic fibrosis transmembrane conductance regulator | Family | |
IPR025837 | CFTR regulator domain | Domain | |
IPR027417 | P-loop containing nucleoside triphosphate hydrolase | Homologous Superfamily | |
IPR003593 | AAA+ ATPase domain | Domain | |
IPR011527 | ABC transporter type 1, transmembrane domain | Domain | |
IPR017871 | ABC transporter-like, conserved site | Conserved Site | |
IPR036640 | ABC transporter type 1, transmembrane domain superfamily | Homologous Superfamily | |
IPR050173 | ATP-binding cassette transporter C-like | Family |