6J24

Crystal structure of a SAM-dependent methyltransferase LepI in complex with its substrate

External Resource: Annotation


Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
A [auth B]Dimerisation2e6j24B2 A: alpha arraysX: HTHH: HTHT: wingedF: Dimerisation2ECOD (1.6)
A [auth B]Methyltransf_11_1e6j24B1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: S-adenosyl-L-methionine-dependent methyltransferasesF: Methyltransf_11_1ECOD (1.6)
B [auth A]Dimerisation2e6j24A1 A: alpha arraysX: HTHH: HTHT: wingedF: Dimerisation2ECOD (1.6)
B [auth A]Methyltransf_11_1e6j24A2 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: S-adenosyl-L-methionine-dependent methyltransferasesF: Methyltransf_11_1ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A [auth B],
B [auth A]		PF00891O-methyltransferase domain (Methyltransf_2)O-methyltransferase domainThis family includes a range of O-methyltransferases. These enzymes utilise S-adenosyl methionine.Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A [auth B],
B [auth A]		O-methyltransferase -

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
A [auth B],
B [auth A]		IPR001077O-methyltransferase domainDomain
A [auth B],
B [auth A]		IPR016461O-methyltransferase COMT-typeFamily
A [auth B],
B [auth A]		IPR029063S-adenosyl-L-methionine-dependent methyltransferase superfamilyHomologous Superfamily
A [auth B],
B [auth A]		IPR036388Winged helix-like DNA-binding domain superfamilyHomologous Superfamily
A [auth B],
B [auth A]		IPR036390Winged helix DNA-binding domain superfamilyHomologous Superfamily