Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
Ad6jd0a_ Alpha and beta proteins (a+b) Cysteine proteinases Cysteine proteinases Papain-like automated matches Human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B SuperfamilyCysteine proteinases 8034025 3001808 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AInhibitor_I29e6jd0A2 A: alpha arraysX: Peptidase inhibitors family I29 (From Topology)H: Peptidase inhibitors family I29 (From Topology)T: Peptidase inhibitors family I29F: Inhibitor_I29ECOD (1.6)
APeptidase_C1e6jd0A1 A: a+b complex topologyX: Cysteine proteinases-likeH: Cysteine proteinases (From Topology)T: Cysteine proteinasesF: Peptidase_C1ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B Chain ACATH (utative)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
PF08246Cathepsin propeptide inhibitor domain (I29) (Inhibitor_I29)Cathepsin propeptide inhibitor domain (I29)This domain is found at the N-terminus of some C1 peptidases such as Cathepsin L where it acts as a propeptide. There are also a number of proteins that are composed solely of multiple copies of this domain such as the peptidase inhibitor salarin Sw ...This domain is found at the N-terminus of some C1 peptidases such as Cathepsin L where it acts as a propeptide. There are also a number of proteins that are composed solely of multiple copies of this domain such as the peptidase inhibitor salarin Swiss:Q70SU8. This family is classified as I29 by MEROPS.
Domain
PF00112Papain family cysteine protease (Peptidase_C1)Papain family cysteine protease- Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
Cathepsin L1