Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
BSCOP2B SuperfamilyMetalloproteases (zincins), catalytic domain 8037105 3001975 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyMetalloproteases (zincins), catalytic domain 8037105 3001975 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
ASNFe6m18A1 A: alpha complex topologyX: Sodium:neurotransmitter symporter family (SNF)-like (From Topology)H: Sodium:neurotransmitter symporter family (SNF)-like (From Topology)T: Sodium:neurotransmitter symporter family (SNF)-likeF: SNFECOD (1.6)
CSNFe6m18C1 A: alpha complex topologyX: Sodium:neurotransmitter symporter family (SNF)-like (From Topology)H: Sodium:neurotransmitter symporter family (SNF)-like (From Topology)T: Sodium:neurotransmitter symporter family (SNF)-likeF: SNFECOD (1.6)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
B, D
PF16959Renal amino acid transporter (Collectrin)Renal amino acid transporterCollectrin is a single-pass transmembrane protein that is homologous to the C-terminal region of human angiotensin-converting enzyme 2, ACE2, SwissProt:Q9BYF1, found in Peptidase_M2 Pfam:PF01401 [1]. Collectrin is critical for normal amino acid reabs ...Collectrin is a single-pass transmembrane protein that is homologous to the C-terminal region of human angiotensin-converting enzyme 2, ACE2, SwissProt:Q9BYF1, found in Peptidase_M2 Pfam:PF01401 [1]. Collectrin is critical for normal amino acid reabsorption in the kidney [2].
Domain
A, C
PF00209Sodium:neurotransmitter symporter family (SNF)Sodium:neurotransmitter symporter family- Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
B, D
Angiotensin-converting enzyme 2
A, C
Sodium-dependent neutral amino acid transporter B(0)AT1

Pharos: Disease Associations Pharos Homepage Annotation

ChainsDrug Target  Associated Disease
B, D
PharosQ9BYF1
A, C
PharosQ695T7