6O4L
Structure of ALDH7A1 mutant E399D complexed with NAD
External Resource: Annotation
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | d6o4la_ | Alpha and beta proteins (a/b) | ALDH-like | ALDH-like | automated matches | automated matches | Human (Homo sapiens ) [TaxId: 9606 ], | SCOPe (2.08) |
B | d6o4lb_ | Alpha and beta proteins (a/b) | ALDH-like | ALDH-like | automated matches | automated matches | Human (Homo sapiens ) [TaxId: 9606 ], | SCOPe (2.08) |
C | d6o4lc_ | Alpha and beta proteins (a/b) | ALDH-like | ALDH-like | automated matches | automated matches | Human (Homo sapiens ) [TaxId: 9606 ], | SCOPe (2.08) |
D | d6o4ld_ | Alpha and beta proteins (a/b) | ALDH-like | ALDH-like | automated matches | automated matches | Human (Homo sapiens ) [TaxId: 9606 ], | SCOPe (2.08) |
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
A | SCOP2B Superfamily | ALDH-like | 8065638 | 3001479 | SCOP2B (2022-06-29) |
B | SCOP2B Superfamily | ALDH-like | 8065638 | 3001479 | SCOP2B (2022-06-29) |
C | SCOP2B Superfamily | ALDH-like | 8065638 | 3001479 | SCOP2B (2022-06-29) |
D | SCOP2B Superfamily | ALDH-like | 8065638 | 3001479 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | Aldedh_2nd | e6o4lA2 | A: a/b three-layered sandwiches | X: ALDH-like (From Topology) | H: ALDH-like (From Topology) | T: ALDH-like | F: Aldedh_2nd | ECOD (1.6) |
A | Aldedh_1st_1 | e6o4lA1 | A: a/b three-layered sandwiches | X: ALDH-like (From Topology) | H: ALDH-like (From Topology) | T: ALDH-like | F: Aldedh_1st_1 | ECOD (1.6) |
B | Aldedh_2nd | e6o4lB2 | A: a/b three-layered sandwiches | X: ALDH-like (From Topology) | H: ALDH-like (From Topology) | T: ALDH-like | F: Aldedh_2nd | ECOD (1.6) |
B | Aldedh_1st_1 | e6o4lB1 | A: a/b three-layered sandwiches | X: ALDH-like (From Topology) | H: ALDH-like (From Topology) | T: ALDH-like | F: Aldedh_1st_1 | ECOD (1.6) |
C | Aldedh_2nd | e6o4lC2 | A: a/b three-layered sandwiches | X: ALDH-like (From Topology) | H: ALDH-like (From Topology) | T: ALDH-like | F: Aldedh_2nd | ECOD (1.6) |
C | Aldedh_1st_1 | e6o4lC1 | A: a/b three-layered sandwiches | X: ALDH-like (From Topology) | H: ALDH-like (From Topology) | T: ALDH-like | F: Aldedh_1st_1 | ECOD (1.6) |
D | Aldedh_2nd | e6o4lD1 | A: a/b three-layered sandwiches | X: ALDH-like (From Topology) | H: ALDH-like (From Topology) | T: ALDH-like | F: Aldedh_2nd | ECOD (1.6) |
D | Aldedh_1st_1 | e6o4lD2 | A: a/b three-layered sandwiches | X: ALDH-like (From Topology) | H: ALDH-like (From Topology) | T: ALDH-like | F: Aldedh_1st_1 | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A | 3.40.605.10 | Alpha Beta | 3-Layer(aba) Sandwich | Aldehyde Dehydrogenase | Chain A, domain 1 | CATH (utative) |
A | 3.40.309.10 | Alpha Beta | 3-Layer(aba) Sandwich | Aldehyde Dehydrogenase | Chain A, domain 2 | CATH (utative) |
B | 3.40.605.10 | Alpha Beta | 3-Layer(aba) Sandwich | Aldehyde Dehydrogenase | Chain A, domain 1 | CATH (utative) |
B | 3.40.309.10 | Alpha Beta | 3-Layer(aba) Sandwich | Aldehyde Dehydrogenase | Chain A, domain 2 | CATH (utative) |
C | 3.40.605.10 | Alpha Beta | 3-Layer(aba) Sandwich | Aldehyde Dehydrogenase | Chain A, domain 1 | CATH (utative) |
C | 3.40.309.10 | Alpha Beta | 3-Layer(aba) Sandwich | Aldehyde Dehydrogenase | Chain A, domain 2 | CATH (utative) |
D | 3.40.605.10 | Alpha Beta | 3-Layer(aba) Sandwich | Aldehyde Dehydrogenase | Chain A, domain 1 | CATH (utative) |
D | 3.40.309.10 | Alpha Beta | 3-Layer(aba) Sandwich | Aldehyde Dehydrogenase | Chain A, domain 2 | CATH (utative) |
Protein Family Annotation Pfam Database Homepage
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR015590 | Aldehyde dehydrogenase domain | Domain | |
IPR016161 | Aldehyde/histidinol dehydrogenase | Homologous Superfamily | |
IPR016162 | Aldehyde dehydrogenase, N-terminal | Homologous Superfamily | |
IPR044638 | Aldehyde dehydrogenase family 7 member A1-like | Family | |
IPR029510 | Aldehyde dehydrogenase, glutamic acid active site | Conserved Site | |
IPR016163 | Aldehyde dehydrogenase, C-terminal | Homologous Superfamily |