Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B SuperfamilyPLP-dependent transferases 8100378 3000954 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyPLP-dependent transferases 8100378 3000954 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyPLP-dependent transferases 8100378 3000954 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyPLP-dependent transferases 8100378 3000954 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
ASHMTe6smnA1 A: a+b two layersX: C-terminal domain in some PLP-dependent transferases (From Topology)H: C-terminal domain in some PLP-dependent transferases (From Topology)T: C-terminal domain in some PLP-dependent transferasesF: SHMTECOD (1.6)
AAminotran_5_Ne6smnA2 A: a/b three-layered sandwichesX: PLP-dependent transferases (From Topology)H: PLP-dependent transferases (From Topology)T: PLP-dependent transferasesF: Aminotran_5_NECOD (1.6)
BSHMTe6smnB1 A: a+b two layersX: C-terminal domain in some PLP-dependent transferases (From Topology)H: C-terminal domain in some PLP-dependent transferases (From Topology)T: C-terminal domain in some PLP-dependent transferasesF: SHMTECOD (1.6)
BAminotran_5_Ne6smnB2 A: a/b three-layered sandwichesX: PLP-dependent transferases (From Topology)H: PLP-dependent transferases (From Topology)T: PLP-dependent transferasesF: Aminotran_5_NECOD (1.6)
CSHMTe6smnC1 A: a+b two layersX: C-terminal domain in some PLP-dependent transferases (From Topology)H: C-terminal domain in some PLP-dependent transferases (From Topology)T: C-terminal domain in some PLP-dependent transferasesF: SHMTECOD (1.6)
CAminotran_5_Ne6smnC2 A: a/b three-layered sandwichesX: PLP-dependent transferases (From Topology)H: PLP-dependent transferases (From Topology)T: PLP-dependent transferasesF: Aminotran_5_NECOD (1.6)
DSHMTe6smnD2 A: a+b two layersX: C-terminal domain in some PLP-dependent transferases (From Topology)H: C-terminal domain in some PLP-dependent transferases (From Topology)T: C-terminal domain in some PLP-dependent transferasesF: SHMTECOD (1.6)
DAminotran_5_Ne6smnD1 A: a/b three-layered sandwichesX: PLP-dependent transferases (From Topology)H: PLP-dependent transferases (From Topology)T: PLP-dependent transferasesF: Aminotran_5_NECOD (1.6)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B, C
PF00464Serine hydroxymethyltransferase (SHMT)Serine hydroxymethyltransferase- Domain
PF00464Serine hydroxymethyltransferase (SHMT)Serine hydroxymethyltransferase- Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B, C
Serine hydroxymethyltransferase 2, mitochondrial
Serine hydroxymethyltransferase 2, mitochondrial

Protein Modification Annotation

Modified Residue(s)
ChainResidue(s)Description
LLP Parent Component: LYS

RESIDAA0119

PSI-MOD :  N6-pyridoxal phosphate-L-lysine MOD:00128