Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B SuperfamilyERAP1, insert domain 8054110 3002272 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyMetalloproteases (zincins), catalytic domain 8054109 3001975 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyLeukotriene A4 hydrolase N-terminal domain 8054108 3000390 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyARM repeat-like 8054111 3000116 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyMetalloproteases (zincins), catalytic domain 8054109 3001975 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyERAP1, insert domain 8054110 3002272 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyARM repeat-like 8054111 3000116 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyLeukotriene A4 hydrolase N-terminal domain 8054108 3000390 SCOP2B (2022-06-29)
CSCOP2B SuperfamilySARS coronavirus receptor-binding domain-like 8093788 3001706 SCOP2B (2022-06-29)
DSCOP2 FamilyHCov-NL63 receptor-binding domain-like 8093787 4006418 SCOP2 (2022-06-29)
DSCOP2 SuperfamilySARS coronavirus receptor-binding domain-like 8093788 3001706 SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AERAP1_Ce6u7fA1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: ERAP1_CECOD (1.6)
APeptidase_M1_2e6u7fA2 A: beta sandwichesX: Baculovirus p35 protein-related (From Topology)H: Baculovirus p35 protein-related (From Topology)T: Baculovirus p35 protein-relatedF: Peptidase_M1_2ECOD (1.6)
AERAP1_Ce6u7fA3 A: alpha superhelicesX: Repetitive alpha hairpinsH: ARM repeat (From Topology)T: ARM repeatF: ERAP1_CECOD (1.6)
APeptidase_M1e6u7fA4 A: mixed a+b and a/bX: Zincin-likeH: Metalloproteases (zincins) catalytic domain (From Topology)T: Metalloproteases (zincins) catalytic domainF: Peptidase_M1ECOD (1.6)
BERAP1_Ce6u7fB2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: ERAP1_CECOD (1.6)
BPeptidase_M1_2e6u7fB4 A: beta sandwichesX: Baculovirus p35 protein-related (From Topology)H: Baculovirus p35 protein-related (From Topology)T: Baculovirus p35 protein-relatedF: Peptidase_M1_2ECOD (1.6)
BERAP1_Ce6u7fB1 A: alpha superhelicesX: Repetitive alpha hairpinsH: ARM repeat (From Topology)T: ARM repeatF: ERAP1_CECOD (1.6)
BPeptidase_M1e6u7fB3 A: mixed a+b and a/bX: Zincin-likeH: Metalloproteases (zincins) catalytic domain (From Topology)T: Metalloproteases (zincins) catalytic domainF: Peptidase_M1ECOD (1.6)
CCorona_S1_2nde6u7fC1 A: a+b three layersX: Coronavirus spike protein receptor-binding domain (From Homology)H: Coronavirus spike protein receptor-binding domainT: Alpha-coronavirus spike protein receptor-binding domainF: Corona_S1_2ndECOD (1.6)
DCorona_S1_2nde6u7fD1 A: a+b three layersX: Coronavirus spike protein receptor-binding domain (From Homology)H: Coronavirus spike protein receptor-binding domainT: Alpha-coronavirus spike protein receptor-binding domainF: Corona_S1_2ndECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A2.60.40.1730 Mainly Beta Sandwich Immunoglobulin-like tricorn interacting facor f3 domainCATH (utative)
A1.10.390.10 Mainly Alpha Orthogonal Bundle Neutral Protease domain 2CATH (utative)
A2.60.40.1910 Mainly Beta Sandwich Immunoglobulin-like CATH (utative)
A1.25.50.20 Mainly Alpha Alpha Horseshoe Zincin-like fold CATH (utative)
B2.60.40.1730 Mainly Beta Sandwich Immunoglobulin-like tricorn interacting facor f3 domainCATH (utative)
B1.10.390.10 Mainly Alpha Orthogonal Bundle Neutral Protease domain 2CATH (utative)
B2.60.40.1910 Mainly Beta Sandwich Immunoglobulin-like CATH (utative)
B1.25.50.20 Mainly Alpha Alpha Horseshoe Zincin-like fold CATH (utative)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B
PF11838ERAP1-like C-terminal domain (ERAP1_C)ERAP1-like C-terminal domainThis large domain is composed of 16 alpha helices organized as 8 HEAT-like repeats. This domain forms a concave face that faces towards the active site of the peptidase.Domain
A, B
PF01433Peptidase family M1 domain (Peptidase_M1)Peptidase family M1 domainMembers of this family are aminopeptidases. The members differ widely in specificity, hydrolysing acidic, basic or neutral N-terminal residues. This family includes leukotriene-A4 hydrolase Swiss:P09960, this enzyme also has an aminopeptidase activ ...Members of this family are aminopeptidases. The members differ widely in specificity, hydrolysing acidic, basic or neutral N-terminal residues. This family includes leukotriene-A4 hydrolase Swiss:P09960, this enzyme also has an aminopeptidase activity [1].
Domain
A, B
PF17900Peptidase M1 N-terminal domain (Peptidase_M1_N)Peptidase M1 N-terminal domainThis domain is found at the N-terminus of aminopeptidases from the M1 family.Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B
Aminopeptidase N
C, D
Spike glycoprotein-