Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
ADNA_methylase_1e6w8jA1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: S-adenosyl-L-methionine-dependent methyltransferasesF: DNA_methylase_1ECOD (1.6)
DDNA_methylase_1e6w8jD1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: S-adenosyl-L-methionine-dependent methyltransferasesF: DNA_methylase_1ECOD (1.6)
BDNA_methylase_1e6w8jB1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: S-adenosyl-L-methionine-dependent methyltransferasesF: DNA_methylase_1ECOD (1.6)
CDNA_methylase_1e6w8jC1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: S-adenosyl-L-methionine-dependent methyltransferasesF: DNA_methylase_1ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
B3.40.50.150 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold Vaccinia Virus protein VP39CATH (utative)
C3.40.50.150 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold Vaccinia Virus protein VP39CATH (utative)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, D
PF00145C-5 cytosine-specific DNA methylase (DNA_methylase)C-5 cytosine-specific DNA methylase- Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, D
DNA (cytosine-5)-methyltransferase 3A
B, C
DNA (cytosine-5)-methyltransferase 3-like
E, F
CAG DNA (25-MER)---

Pharos: Disease Associations Pharos Homepage Annotation

ChainsDrug Target  Associated Disease
A, D
PharosQ9Y6K1
B, C
PharosQ9UJW3