Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
APro_dhe6x99A2 A: a/b barrelsX: TIM beta/alpha-barrelH: TIM barrels (From Topology)T: TIM barrelsF: Pro_dhECOD (1.6)
AF_UNCLASSIFIEDe6x99A3 A: a/b three-layered sandwichesX: ALDH-like (From Topology)H: ALDH-like (From Topology)T: ALDH-likeF: F_UNCLASSIFIEDECOD (1.6)
AAldedh_2nde6x99A5 A: a/b three-layered sandwichesX: ALDH-like (From Topology)H: ALDH-like (From Topology)T: ALDH-likeF: Aldedh_2ndECOD (1.6)
AAldedh_1st_1e6x99A4 A: a/b three-layered sandwichesX: ALDH-like (From Topology)H: ALDH-like (From Topology)T: ALDH-likeF: Aldedh_1st_1ECOD (1.6)
AputA_2nd,Pro_dh-DNA_bdge6x99A1 A: extended segmentsX: N-terminal domain of bifunctional PutA protein (From Topology)H: N-terminal domain of bifunctional PutA protein (From Topology)T: N-terminal domain of bifunctional PutA proteinF: putA_2nd,Pro_dh-DNA_bdgECOD (1.6)
BPro_dhe6x99B2 A: a/b barrelsX: TIM beta/alpha-barrelH: TIM barrels (From Topology)T: TIM barrelsF: Pro_dhECOD (1.6)
BF_UNCLASSIFIEDe6x99B5 A: a/b three-layered sandwichesX: ALDH-like (From Topology)H: ALDH-like (From Topology)T: ALDH-likeF: F_UNCLASSIFIEDECOD (1.6)
BAldedh_2nde6x99B4 A: a/b three-layered sandwichesX: ALDH-like (From Topology)H: ALDH-like (From Topology)T: ALDH-likeF: Aldedh_2ndECOD (1.6)
BAldedh_1st_1e6x99B1 A: a/b three-layered sandwichesX: ALDH-like (From Topology)H: ALDH-like (From Topology)T: ALDH-likeF: Aldedh_1st_1ECOD (1.6)
BputA_2nd,Pro_dh-DNA_bdge6x99B3 A: extended segmentsX: N-terminal domain of bifunctional PutA protein (From Topology)H: N-terminal domain of bifunctional PutA protein (From Topology)T: N-terminal domain of bifunctional PutA proteinF: putA_2nd,Pro_dh-DNA_bdgECOD (1.6)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B
PF00171Aldehyde dehydrogenase family (Aldedh)Aldehyde dehydrogenase family- Family
A, B
PF01619Proline dehydrogenase (Pro_dh)Proline dehydrogenase- Family
A, B
PF18327Proline utilization A proline dehydrogenase N-terminal domain (PRODH)Proline utilization A proline dehydrogenase N-terminal domainThis is the N-terminal domain found in Proline utilization A (PutA) proteins. Proline utilization A (PutA) is a flavoprotein that has mutually exclusive roles as a transcriptional repressor of the put regulon and a membrane-associated enzyme that cat ...This is the N-terminal domain found in Proline utilization A (PutA) proteins. Proline utilization A (PutA) is a flavoprotein that has mutually exclusive roles as a transcriptional repressor of the put regulon and a membrane-associated enzyme that catalyzes the oxidation of proline to glutamate [4]. The N-terminal region carries the flavoenzyme proline dehydrogenase (PRODH) domain which catalyzes the 2-electron oxidation of proline with the concomitant reduction of a flavin cofactor [9].
Domain
A, B
PF14850DNA-binding domain of Proline dehydrogenase (Pro_dh-DNA_bdg)DNA-binding domain of Proline dehydrogenaseThis domain lies at the N-terminus of bifunctional proline-dehydrogenases and is found to bind DNA.Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B
Bifunctional protein PutA