6Z5O
CRYSTAL STRUCTURE OF RAT PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE-1 (RPMFE1) COMPLEXED WITH COENZYME-A AND OXIDISED NICOTINAMIDE ADENINE DINUCLEOTIDE
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A [auth AAA] | 3HCDH | e6z5oAAA1 | A: alpha arrays | X: 6-phosphogluconate dehydrogenase C-terminal domain-like (From Topology) | H: 6-phosphogluconate dehydrogenase C-terminal domain-like (From Topology) | T: 6-phosphogluconate dehydrogenase C-terminal domain-like | F: 3HCDH | ECOD (1.6) |
A [auth AAA] | 3HCDH_N | e6z5oAAA3 | A: a/b three-layered sandwiches | X: Rossmann-like | H: Rossmann-related | T: NAD(P)-binding Rossmann-fold domains | F: 3HCDH_N | ECOD (1.6) |
A [auth AAA] | ECH_1 | e6z5oAAA2 | A: a/b three-layered sandwiches | X: ClpP/crotonase (From Topology) | H: ClpP/crotonase (From Topology) | T: ClpP/crotonase | F: ECH_1 | ECOD (1.6) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
A [auth AAA] | PF02737 | 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain (3HCDH_N) | 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain | This family also includes lambda crystallin. | Domain |
A [auth AAA] | PF00725 | 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain (3HCDH) | 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain | This family also includes lambda crystallin. Some proteins include two copies of this domain. | Domain |
A [auth AAA] | PF00378 | Enoyl-CoA hydratase/isomerase (ECH_1) | Enoyl-CoA hydratase/isomerase | This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
A [auth AAA] | IPR001753 | Enoyl-CoA hydratase/isomerase | Family |
A [auth AAA] | IPR029045 | ClpP/crotonase-like domain superfamily | Homologous Superfamily |
A [auth AAA] | IPR018376 | Enoyl-CoA hydratase/isomerase, conserved site | Conserved Site |
A [auth AAA] | IPR008927 | 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily | Homologous Superfamily |
A [auth AAA] | IPR006108 | 3-hydroxyacyl-CoA dehydrogenase, C-terminal | Domain |
A [auth AAA] | IPR036291 | NAD(P)-binding domain superfamily | Homologous Superfamily |
A [auth AAA] | IPR006180 | 3-hydroxyacyl-CoA dehydrogenase, conserved site | Conserved Site |
A [auth AAA] | IPR006176 | 3-hydroxyacyl-CoA dehydrogenase, NAD binding | Domain |