Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
C [auth A]SCOP2B Superfamily(Trans)glycosidases 8090457 3000313 SCOP2B (2022-06-29)
C [auth A]SCOP2B SuperfamilyGlycosyl hydrolase domain-like 8090459 3001528 SCOP2B (2022-06-29)
C [auth A]SCOP2B SuperfamilyYicI C-terminal domain-like 8090453 3000267 SCOP2B (2022-06-29)
G [auth C]SCOP2B Superfamily(Trans)glycosidases 8090457 3000313 SCOP2B (2022-06-29)
G [auth C]SCOP2B SuperfamilyGlycosyl hydrolase domain-like 8090459 3001528 SCOP2B (2022-06-29)
G [auth C]SCOP2B SuperfamilyYicI C-terminal domain-like 8090453 3000267 SCOP2B (2022-06-29)
D [auth B]SCOP2B SuperfamilyEGF/Laminin-like 8106404 3000412 SCOP2B (2022-06-29)
H [auth D]SCOP2B SuperfamilyEGF/Laminin-like 8106403 3000412 SCOP2B (2022-06-29)
H [auth D]SCOP2B SuperfamilyEGF/Laminin-like 8106404 3000412 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
C [auth A]Glyco_hydro_31_Ce7kbjA3 A: beta sandwichesX: Glycosyl hydrolase domain-likeH: Glycosyl hydrolase domain (From Topology)T: Glycosyl hydrolase domainF: Glyco_hydro_31_CECOD (1.6)
C [auth A]DUF5110_1e7kbjA2 A: beta sandwichesX: Putative glucosidase YicI, C-terminal domain (From Topology)H: Putative glucosidase YicI, C-terminal domain (From Topology)T: Putative glucosidase YicI, C-terminal domainF: DUF5110_1ECOD (1.6)
C [auth A]Glyco_hydro_31_Ne7kbjA1 A: a/b barrelsX: TIM beta/alpha-barrelH: TIM barrels (From Topology)T: TIM barrelsF: Glyco_hydro_31_NECOD (1.6)
G [auth C]Glyco_hydro_31_Ce7kbjC3 A: beta sandwichesX: Glycosyl hydrolase domain-likeH: Glycosyl hydrolase domain (From Topology)T: Glycosyl hydrolase domainF: Glyco_hydro_31_CECOD (1.6)
G [auth C]DUF5110_1e7kbjC2 A: beta sandwichesX: Putative glucosidase YicI, C-terminal domain (From Topology)H: Putative glucosidase YicI, C-terminal domain (From Topology)T: Putative glucosidase YicI, C-terminal domainF: DUF5110_1ECOD (1.6)
G [auth C]Glyco_hydro_31_Ne7kbjC1 A: a/b barrelsX: TIM beta/alpha-barrelH: TIM barrels (From Topology)T: TIM barrelsF: Glyco_hydro_31_NECOD (1.6)
D [auth B]PRKCSH-likee7kbjB1 A: few secondary structure elementsX: EGF-likeH: LDL receptor-like module (From Topology)T: LDL receptor-like moduleF: PRKCSH-likeECOD (1.6)
H [auth D]PRKCSH-likee7kbjD1 A: few secondary structure elementsX: EGF-likeH: LDL receptor-like module (From Topology)T: LDL receptor-like moduleF: PRKCSH-likeECOD (1.6)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A [auth G],
E [auth I]
PF13802Glycosyl hydrolase 31 N-terminal galactose mutarotase-like domain (Gal_mutarotas_2)Glycosyl hydrolase 31 N-terminal galactose mutarotase-like domainThis entry represents the first of three common domains found in Glycosyl hydrolase 31 family proteins. It has a galactose mutarotase superfamily fold.Domain
B [auth H],
F [auth J]
PF13802Glycosyl hydrolase 31 N-terminal galactose mutarotase-like domain (Gal_mutarotas_2)Glycosyl hydrolase 31 N-terminal galactose mutarotase-like domainThis entry represents the first of three common domains found in Glycosyl hydrolase 31 family proteins. It has a galactose mutarotase superfamily fold.Domain
C [auth A],
G [auth C]
PF21365Glycosyl hydrolase family 31 C-terminal domain (Glyco_hydro_31_3rd)Glycosyl hydrolase family 31 C-terminal domainGlycosyl hydrolases are key enzymes of carbohydrate metabolism. Family 31 comprises of enzymes that are, or similar to, alpha- galactosidases. This entry represents the 3rd beta sandwich domain.Domain
C [auth A],
G [auth C]
PF01055Glycosyl hydrolases family 31 TIM-barrel domain (Glyco_hydro_31_2nd)Glycosyl hydrolases family 31 TIM-barrel domainGlycosyl hydrolases are key enzymes of carbohydrate metabolism. Family 31 comprises of enzymes that are, or similar to, alpha- galactosidases. This entry corresponds to the second domain of family 31 enzymes and adopts a TIM-barrel fold.Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A [auth G],
E [auth I]
Neutral alpha-glucosidase AB Trypsin-cleaved Fragment #1
B [auth H],
F [auth J]
Neutral alpha-glucosidase AB Trypsin-cleaved Fragment #2
C [auth A],
G [auth C]
Neutral alpha-glucosidase AB Trypsin-cleaved Fragment #3
D [auth B],
H [auth D]
Glucosidase 2 subunit beta

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
A [auth G],
E [auth I]
IPR030459Glycosyl hydrolases family 31, conserved siteConserved Site
A [auth G],
E [auth I]
IPR000322Glycoside hydrolase family 31, TIM barrel domainDomain
A [auth G],
E [auth I]
IPR048395Glycosyl hydrolase family 31, C-terminal domainDomain
A [auth G],
E [auth I]
IPR017853Glycoside hydrolase superfamilyHomologous Superfamily
A [auth G],
E [auth I]
IPR030458Glycosyl hydrolases family 31, active siteActive Site
A [auth G],
E [auth I]
IPR013780Glycosyl hydrolase, all-betaHomologous Superfamily
A [auth G],
E [auth I]
IPR025887Glycoside hydrolase family 31, N-terminal domainDomain
A [auth G],
E [auth I]
IPR011013Galactose mutarotase-like domain superfamilyHomologous Superfamily
B [auth H],
F [auth J]
IPR030459Glycosyl hydrolases family 31, conserved siteConserved Site
B [auth H],
F [auth J]
IPR000322Glycoside hydrolase family 31, TIM barrel domainDomain
B [auth H],
F [auth J]
IPR048395Glycosyl hydrolase family 31, C-terminal domainDomain
B [auth H],
F [auth J]
IPR017853Glycoside hydrolase superfamilyHomologous Superfamily
B [auth H],
F [auth J]
IPR030458Glycosyl hydrolases family 31, active siteActive Site
B [auth H],
F [auth J]
IPR013780Glycosyl hydrolase, all-betaHomologous Superfamily
B [auth H],
F [auth J]
IPR025887Glycoside hydrolase family 31, N-terminal domainDomain
B [auth H],
F [auth J]
IPR011013Galactose mutarotase-like domain superfamilyHomologous Superfamily
C [auth A],
G [auth C]
IPR030459Glycosyl hydrolases family 31, conserved siteConserved Site
C [auth A],
G [auth C]
IPR000322Glycoside hydrolase family 31, TIM barrel domainDomain
C [auth A],
G [auth C]
IPR048395Glycosyl hydrolase family 31, C-terminal domainDomain
C [auth A],
G [auth C]
IPR017853Glycoside hydrolase superfamilyHomologous Superfamily
C [auth A],
G [auth C]
IPR030458Glycosyl hydrolases family 31, active siteActive Site
C [auth A],
G [auth C]
IPR013780Glycosyl hydrolase, all-betaHomologous Superfamily
C [auth A],
G [auth C]
IPR025887Glycoside hydrolase family 31, N-terminal domainDomain
C [auth A],
G [auth C]
IPR011013Galactose mutarotase-like domain superfamilyHomologous Superfamily
D [auth B],
H [auth D]
IPR018247EF-Hand 1, calcium-binding siteBinding Site
D [auth B],
H [auth D]
IPR009011Mannose-6-phosphate receptor binding domain superfamilyHomologous Superfamily
D [auth B],
H [auth D]
IPR028146Glucosidase II beta subunit, N-terminalDomain
D [auth B],
H [auth D]
IPR044865MRH domainDomain
D [auth B],
H [auth D]
IPR036055LDL receptor-like superfamilyHomologous Superfamily
D [auth B],
H [auth D]
IPR036607Glucosidase 2 subunit beta-likeDomain
D [auth B],
H [auth D]
IPR039794Glucosidase II beta subunit-likeFamily
D [auth B],
H [auth D]
IPR002048EF-hand domainDomain
D [auth B],
H [auth D]
IPR011992EF-hand domain pairHomologous Superfamily