7MPG

Cryo-EM structure of Prefusion-stabilized RSV F (DS-Cav1) in complex with Fab AM14


Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
D [auth F]C1-set_1e7mpgF2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_1ECOD (1.6)
D [auth F]V-set_12e7mpgF1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-set_12ECOD (1.6)
F [auth H]C1-set_1e7mpgH2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_1ECOD (1.6)
F [auth H]V-set_12e7mpgH1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-set_12ECOD (1.6)
H [auth D]C1-set_1e7mpgD2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_1ECOD (1.6)
H [auth D]V-set_12e7mpgD1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-set_12ECOD (1.6)
E [auth G]C1-set_4e7mpgG2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_4ECOD (1.6)
E [auth G]V-sete7mpgG1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-setECOD (1.6)
G [auth I]C1-set_4e7mpgI2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_4ECOD (1.6)
G [auth I]V-sete7mpgI1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-setECOD (1.6)
I [auth E]C1-set_4e7mpgE2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_4ECOD (1.6)
I [auth E]V-sete7mpgE1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-setECOD (1.6)
AFusion_glye7mpgA1 A: a+b complex topologyX: Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein (From Topology)H: Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein (From Topology)T: Head and neck region of the ectodomain of paramyxoviruses fusion glycoproteinF: Fusion_glyECOD (1.6)
BFusion_glye7mpgB1 A: a+b complex topologyX: Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein (From Topology)H: Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein (From Topology)T: Head and neck region of the ectodomain of paramyxoviruses fusion glycoproteinF: Fusion_glyECOD (1.6)
CFusion_glye7mpgC1 A: a+b complex topologyX: Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein (From Topology)H: Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein (From Topology)T: Head and neck region of the ectodomain of paramyxoviruses fusion glycoproteinF: Fusion_glyECOD (1.6)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B, C
PF00523Fusion glycoprotein F0 (Fusion_gly)Fusion glycoprotein F0- Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
D [auth F],
F [auth H],
H [auth D]
AM14 Fab Heavy Chain---
E [auth G],
G [auth I],
I [auth E]
AM14 Fab Light Chain---
A, B, C
Fusion glycoprotein F0,Envelope glycoprotein

InterPro: Protein Family Classification InterPro Database Homepage