Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AACPSe7n8mA2 A: a+b three layersX: Bacillus chorismate mutase-likeH: 4'-phosphopantetheinyl transferase (From Topology)T: 4'-phosphopantetheinyl transferaseF: ACPSECOD (1.6)
AEntDe7n8mA1 A: a+b three layersX: Bacillus chorismate mutase-likeH: 4'-phosphopantetheinyl transferase (From Topology)T: 4'-phosphopantetheinyl transferaseF: EntDECOD (1.6)
BACPSe7n8mB1 A: a+b three layersX: Bacillus chorismate mutase-likeH: 4'-phosphopantetheinyl transferase (From Topology)T: 4'-phosphopantetheinyl transferaseF: ACPSECOD (1.6)
BEntDe7n8mB2 A: a+b three layersX: Bacillus chorismate mutase-likeH: 4'-phosphopantetheinyl transferase (From Topology)T: 4'-phosphopantetheinyl transferaseF: EntDECOD (1.6)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B
PF178374'-phosphopantetheinyl transferase N-terminal domain (4PPT_N)4'-phosphopantetheinyl transferase N-terminal domainThis entry represents the N-terminal domain from 4'- phosphopantetheinyl transferase enzymes. This domain is structurally related to the Pfam:PF01648 domain with which it forms a pseudodimeric arrangement [2].Domain
A, B
PF016484'-phosphopantetheinyl transferase superfamily (ACPS)4'-phosphopantetheinyl transferase superfamilyMembers of this family transfers the 4'-phosphopantetheine (4'-PP) moiety from coenzyme A (CoA) to the invariant serine of Pfam:PF00550. This post-translational modification renders holo-ACP capable of acyl group activation via thioesterification of ...Members of this family transfers the 4'-phosphopantetheine (4'-PP) moiety from coenzyme A (CoA) to the invariant serine of Pfam:PF00550. This post-translational modification renders holo-ACP capable of acyl group activation via thioesterification of the cysteamine thiol of 4'-PP [1]. This superfamily consists of two subtypes: The ACPS type such as Swiss:P24224 and the Sfp type such as Swiss:P39135. The structure of the Sfp type is known [3], which shows the active site accommodates a magnesium ion. The most highly conserved regions of the alignment are involved in binding the magnesium ion.
Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B
4'-phosphopantetheinyl transferase PptT