7VHE
Crystal structure of the STX2a complexed with RRRA peptide
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
A | SCOP2B Superfamily | Ribosome inactivating proteins (RIP) | 8099972 | 3001164 | SCOP2B (2022-06-29) |
B | SCOP2B Superfamily | Bacterial enterotoxins | 8097164 | 3000434 | SCOP2B (2022-06-29) |
C | SCOP2B Superfamily | Bacterial enterotoxins | 8097164 | 3000434 | SCOP2B (2022-06-29) |
D | SCOP2B Superfamily | Bacterial enterotoxins | 8097164 | 3000434 | SCOP2B (2022-06-29) |
E | SCOP2B Superfamily | Bacterial enterotoxins | 8097164 | 3000434 | SCOP2B (2022-06-29) |
F | SCOP2B Superfamily | Bacterial enterotoxins | 8097164 | 3000434 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | RIP | e7vheA1 | A: a+b two layers | X: RIP/Polo-box domain | H: Ribosome inactivating proteins (RIP) (From Topology) | T: Ribosome inactivating proteins (RIP) | F: RIP | ECOD (1.6) |
B | SLT_beta | e7vheB1 | A: beta barrels | X: OB-fold | H: Bacterial enterotoxins (From Topology) | T: Bacterial enterotoxins | F: SLT_beta | ECOD (1.6) |
C | SLT_beta | e7vheC1 | A: beta barrels | X: OB-fold | H: Bacterial enterotoxins (From Topology) | T: Bacterial enterotoxins | F: SLT_beta | ECOD (1.6) |
D | SLT_beta | e7vheD1 | A: beta barrels | X: OB-fold | H: Bacterial enterotoxins (From Topology) | T: Bacterial enterotoxins | F: SLT_beta | ECOD (1.6) |
E | SLT_beta | e7vheE1 | A: beta barrels | X: OB-fold | H: Bacterial enterotoxins (From Topology) | T: Bacterial enterotoxins | F: SLT_beta | ECOD (1.6) |
F | SLT_beta | e7vheF1 | A: beta barrels | X: OB-fold | H: Bacterial enterotoxins (From Topology) | T: Bacterial enterotoxins | F: SLT_beta | ECOD (1.6) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF00161 | Ribosome inactivating protein (RIP) | Ribosome inactivating protein | - | Domain | |
PF02258 | Shiga-like toxin beta subunit (SLT_beta) | Shiga-like toxin beta subunit | This family represents the B subunit of shiga-like toxin (SLT or verotoxin) produced by some strains of E.coli associated with hemorrhagic colitis and hemolytic uremic syndrome. SLT's are composed of one enzymatic A subunit and five cell binding B s ... | Domain | |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR036041 | Ribosome-inactivating protein superfamily | Homologous Superfamily | |
IPR016331 | Shiga-like toxin, subunit A | Family | |
IPR017988 | Ribosome-inactivating protein conserved site | Conserved Site | |
IPR016139 | Ribosome-inactivating protein, subdomain 2 | Homologous Superfamily | |
IPR016138 | Ribosome-inactivating protein, subdomain 1 | Homologous Superfamily | |
IPR001574 | Ribosome-inactivating protein | Family | |
IPR008992 | Enterotoxin | Homologous Superfamily | |
IPR003189 | Shiga-like toxin, beta subunit | Family |
Protein Modification Annotation
Modified Residue(s) | ||
---|---|---|
Chain | Residue(s) | Description |
NH2 | AA0081 , AA0083 , AA0084 , AA0086 , AA0087 , AA0088 , AA0090 , AA0091 , AA0092 , AA0093 , AA0095 , AA0096 , AA0097 , AA0098 , AA0099 , AA0100 :  L-alanine amide MOD:00090 , L-asparagine amide MOD:00092 , L-aspartic acid 1-amide MOD:00093 , L-glutamine amide MOD:00095 , L-glutamic acid 1-amide MOD:00096 , glycine amide MOD:00097 , L-isoleucine amide MOD:00099 , L-leucine amide MOD:00100 , L-lysine amide MOD:00101 , L-methionine amide MOD:00102 , L-proline amide MOD:00104 , L-serine amide MOD:00105 , L-threonine amide MOD:00106 , L-tryptophan amide MOD:00107 , L-tyrosine amide MOD:00108 , L-valine amide MOD:00109 | :