Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
APro_dhe8dkoA1 A: a/b barrelsX: TIM beta/alpha-barrelH: TIM barrels (From Topology)T: TIM barrelsF: Pro_dhECOD (1.6)
AputA_2nde8dkoA2 A: extended segmentsX: N-terminal domain of bifunctional PutA protein (From Topology)H: N-terminal domain of bifunctional PutA protein (From Topology)T: N-terminal domain of bifunctional PutA proteinF: putA_2ndECOD (1.6)
BPro_dhe8dkoB1 A: a/b barrelsX: TIM beta/alpha-barrelH: TIM barrels (From Topology)T: TIM barrelsF: Pro_dhECOD (1.6)
BputA_2nde8dkoB2 A: extended segmentsX: N-terminal domain of bifunctional PutA protein (From Topology)H: N-terminal domain of bifunctional PutA protein (From Topology)T: N-terminal domain of bifunctional PutA proteinF: putA_2ndECOD (1.6)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B
PF01619Proline dehydrogenase (Pro_dh)Proline dehydrogenase- Family
A, B
PF18327Proline utilization A proline dehydrogenase N-terminal domain (PRODH)Proline utilization A proline dehydrogenase N-terminal domainThis is the N-terminal domain found in Proline utilization A (PutA) proteins. Proline utilization A (PutA) is a flavoprotein that has mutually exclusive roles as a transcriptional repressor of the put regulon and a membrane-associated enzyme that cat ...This is the N-terminal domain found in Proline utilization A (PutA) proteins. Proline utilization A (PutA) is a flavoprotein that has mutually exclusive roles as a transcriptional repressor of the put regulon and a membrane-associated enzyme that catalyzes the oxidation of proline to glutamate [4]. The N-terminal region carries the flavoenzyme proline dehydrogenase (PRODH) domain which catalyzes the 2-electron oxidation of proline with the concomitant reduction of a flavin cofactor [9].
Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B
Bifunctional protein PutA