8H1R

Crystal structure of LptDE-YifL complex

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	LptD-like barrel	8053495	3002195	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	LptD-like barrel	8053495	3002195	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	TolB N-terminal domain-like	8053485	3000482	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	TolB N-terminal domain-like	8053485	3000482	SCOP2B (2022-06-29)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, D	PF03968	LptA/(LptD N-terminal domain) LPS transport protein (LptD_N)	LptA/(LptD N-terminal domain) LPS transport protein	This family of proteins are involved in lipopolysaccharide transport across the gram negative inner and outer membranes. The type examples for this family are E. coli LptA Swiss:P0ADV1 and the N-terminal domain of LptD Swiss:P31554.	Domain
A, D	PF04453	LPS transport system D (LptD)	LPS transport system D	-	Family
B, E	PF04390	Lipopolysaccharide-assembly (LptE)	Lipopolysaccharide-assembly	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, D	LPS-assembly protein LptD	-	membrane organization membrane biogenesis membrane assembly cellular component organization cellular component biogenesis cellular component assembly cellular process cellular component organization or biogenesis cell envelope organization Gram-negative-bacterium-type cell outer membrane assembly external encapsulating structure organization regulation of cellular process cellular biosynthetic process regulation of polysaccharide metabolic process membrane organization membrane biogenesis membrane assembly cellular component organization cellular component biogenesis cellular component assembly cellular process cellular component organization or biogenesis cell envelope organization Gram-negative-bacterium-type cell outer membrane assembly external encapsulating structure organization regulation of cellular process cellular biosynthetic process regulation of polysaccharide metabolic process regulation of primary metabolic process polysaccharide metabolic process regulation of carbohydrate metabolic process regulation of biosynthetic process carbohydrate metabolic process regulation of biological process polysaccharide biosynthetic process carbohydrate biosynthetic process cellular metabolic process biological regulation primary metabolic process regulation of cellular metabolic process regulation of macromolecule metabolic process macromolecule biosynthetic process regulation of cellular biosynthetic process biosynthetic process regulation of polysaccharide biosynthetic process metabolic process regulation of macromolecule biosynthetic process macromolecule metabolic process regulation of carbohydrate biosynthetic process regulation of metabolic process localization transport lipopolysaccharide transport macromolecule localization lipid localization lipid transport carbohydrate derivative transport establishment of localization	cell periphery cell outer membrane external encapsulating structure membrane cell envelope outer membrane cellular anatomical entity
B, E	LPS-assembly lipoprotein LptE	binding lipid binding lipopolysaccharide binding carbohydrate derivative binding	membrane organization membrane biogenesis membrane assembly cellular component organization cellular component biogenesis cellular component assembly cellular process cellular component organization or biogenesis cell envelope organization Gram-negative-bacterium-type cell outer membrane assembly external encapsulating structure organization localization transport lipopolysaccharide transport membrane organization membrane biogenesis membrane assembly cellular component organization cellular component biogenesis cellular component assembly cellular process cellular component organization or biogenesis cell envelope organization Gram-negative-bacterium-type cell outer membrane assembly external encapsulating structure organization localization transport lipopolysaccharide transport macromolecule localization lipid localization lipid transport carbohydrate derivative transport establishment of localization	cell periphery cell outer membrane external encapsulating structure membrane cell envelope outer membrane cellular anatomical entity
C, F	Uncharacterized lipoprotein YifL	-	membrane organization membrane biogenesis membrane assembly cellular component organization cellular component biogenesis cellular component assembly cellular process cellular component organization or biogenesis cell envelope organization Gram-negative-bacterium-type cell outer membrane assembly external encapsulating structure organization	cell periphery plasma membrane membrane cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, D	IPR007543	LptD, C-terminal	Domain
A, D	IPR020889	LPS-assembly protein LptD	Family
A, D	IPR050218	Lipopolysaccharide Assembly Protein LptD	Family
A, D	IPR005653	Organic solvent tolerance-like, N-terminal	Domain
B, E	IPR007485	LPS-assembly lipoprotein LptE	Family
C, F	IPR032831	Prokaryotic lipoprotein-attachment site	Conserved Site

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.