Annotations: 8HTX

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, D [auth B]	PF10523	BEN domain (BEN)	BEN domain	The BEN domain is found in diverse animal proteins such as BANP/SMAR1, NAC1 and the Drosophila mod(mdg4) isoform C, in the chordopoxvirus virosomal protein E5R and in several proteins of polydnaviruses. Computational analysis suggests that the BEN do ...	The BEN domain is found in diverse animal proteins such as BANP/SMAR1, NAC1 and the Drosophila mod(mdg4) isoform C, in the chordopoxvirus virosomal protein E5R and in several proteins of polydnaviruses. Computational analysis suggests that the BEN domain mediates protein-DNA and protein-protein interactions during chromatin organisation and transcription [1]. The BEN domain-containing protein 3 (BEND3) is shown to interact (via BEN domains 1 and 3) with ERCC6L (via N-terminal TPR repeat and SNF2 HeliC region of ERCC6L) which stimulates the ERCC6L translocase and ATPase activities [2].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, D [auth B]	Protein BANP	DNA binding binding organic cyclic compound binding nucleic acid binding identical protein binding protein binding	catabolic process regulation of cellular process negative regulation of biological process macromolecule catabolic process negative regulation of protein catabolic process regulation of primary metabolic process negative regulation of cellular process protein metabolic process negative regulation of protein metabolic process negative regulation of macromolecule metabolic process negative regulation of catabolic process regulation of biological process regulation of protein metabolic process negative regulation of metabolic process catabolic process regulation of cellular process negative regulation of biological process macromolecule catabolic process negative regulation of protein catabolic process regulation of primary metabolic process negative regulation of cellular process protein metabolic process negative regulation of protein metabolic process negative regulation of macromolecule metabolic process negative regulation of catabolic process regulation of biological process regulation of protein metabolic process negative regulation of metabolic process biological regulation primary metabolic process protein catabolic process regulation of macromolecule metabolic process regulation of catabolic process metabolic process cellular process macromolecule metabolic process regulation of metabolic process regulation of protein catabolic process protein localization localization cellular localization protein localization to organelle cellular macromolecule localization macromolecule localization protein localization to nucleus cellular component organization chromatin organization cellular component organization or biogenesis	membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membrane-bounded organelle intracellular organelle lumen nuclear body intracellular organelle cellular anatomical structure nucleoplasm organelle lumen organelle nuclear lumen
B [auth C], C [auth D], E, F	DNA (5'-D(CPTPCPTP(5CM)PGPCPGPAPGPAPG)-3')	-	-	-