8X3H

Crystal structure of iron-bound recombinant ovotransferrin N-lobe at 0.93 angstrom resolution

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Type 2 solute binding protein-like	8033418	3000083	SCOP2B (2022-06-29)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF00405	Transferrin (Transferrin)	Transferrin	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Ovotransferrin	cation binding ferric iron binding transition metal ion binding iron ion binding ion binding binding metal ion binding small molecule binding	response to stimulus response to chemical response to xenobiotic stimulus localization transport iron ion transport transition metal ion transport monoatomic ion transport monoatomic cation transport establishment of localization metal ion transport acute-phase response defense response response to stress response to stimulus response to chemical response to xenobiotic stimulus localization transport iron ion transport transition metal ion transport monoatomic ion transport monoatomic cation transport establishment of localization metal ion transport acute-phase response defense response response to stress inflammatory response acute inflammatory response humoral immune response biological process involved in interspecies interaction between organisms response to other organism immune response defense response to symbiont response to external stimulus antimicrobial humoral response response to biotic stimulus defense response to other organism immune system process response to external biotic stimulus antibacterial humoral response defense response to bacterium response to bacterium cellular localization inorganic ion homeostasis homeostatic process sequestering of metal ion maintenance of location in cell maintenance of location extracellular sequestering of iron ion intracellular iron ion homeostasis cellular homeostasis chemical homeostasis sequestering of iron ion intracellular monoatomic cation homeostasis monoatomic ion homeostasis intracellular chemical homeostasis cellular process monoatomic cation homeostasis intracellular monoatomic ion homeostasis intracellular sequestering of iron ion response to lipid response to oxygen-containing compound response to lipopolysaccharide response to molecule of bacterial origin	membrane-bounded organelle intracellular anatomical structure early endosome endosome intracellular vesicle cellular anatomical entity intracellular membrane-bounded organelle endomembrane system intracellular organelle cytoplasmic vesicle organelle cytoplasm vesicle recycling endosome membrane-bounded organelle intracellular anatomical structure early endosome endosome intracellular vesicle cellular anatomical entity intracellular membrane-bounded organelle endomembrane system intracellular organelle cytoplasmic vesicle organelle cytoplasm vesicle recycling endosome organomineral extracellular matrix cell periphery extracellular matrix external encapsulating structure plasma membrane membrane extracellular region extracellular space

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR016357	Transferrin	Family
A	IPR001156	Transferrin-like domain	Domain
A	IPR018195	Transferrin family, iron binding site	Binding Site

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.