2GP

GUANOSINE-2'-MONOPHOSPHATE

Find entries where: 2GP

is present as a standalone ligand in 41 entries

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Chemical Component Summary
Name	GUANOSINE-2'-MONOPHOSPHATE
Identifiers	[(2R,3R,4R,5R)-2-(2-amino-6-oxo-1H-purin-9-yl)-4-hydroxy-5-(hydroxymethyl)oxolan-3-yl] dihydrogen phosphate
Formula	C₁₀ H₁₄ N₅ O₈ P
Molecular Weight	363.221
Type	NON-POLYMER
Isomeric SMILES	c1nc2c(n1[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)OP(=O)(O)O)N=C(NC2=O)N
InChI	InChI=1S/C10H14N5O8P/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(23-24(19,20)21)5(17)3(1-16)22-9/h2-3,5-6,9,16-17H,1H2,(H2,19,20,21)(H3,11,13,14,18)/t3-,5-,6-,9-/m1/s1
InChIKey	WTIFIAZWCCBCGE-UUOKFMHZSA-N

Chemical Details
Formal Charge	0
Atom Count	38
Chiral Atom Count	4
Bond Count	40
Aromatic Bond Count	5

Drug Info: DrugBank

DrugBank ID	DB01937
Name	Guanosine-2'-monophosphate
Groups	experimental
Synonyms	2'-O-phosphoguanosine 2'-GMP Guanosine 2'-phosphate 2'-guanylic acid Guanosine-2'-monophosphate
Categories	Guanine Nucleotides Heterocyclic Compounds, Fused-Ring Isomerism Nucleic Acids, Nucleotides, and Nucleosides Nucleotides Purine Nucleotides Purines Ribonucleotides
CAS number	130-50-7

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Guanyl-specific ribonuclease Sa	DVSGTVCLSALPPEATDTLNLIASDGPFPYSQDGVVFQNRESVLPTQSYG...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682