2HC

(2E)-3-(2-HYDROXYPHENYL)ACRYLIC ACID

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is present as a standalone ligand in 2 entries

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Chemical Component Summary
Name	(2E)-3-(2-HYDROXYPHENYL)ACRYLIC ACID
Synonyms	TRANS-2-HYDROXYCINNAMIC ACID; O-COUMARIC ACID
Identifiers	(E)-3-(2-hydroxyphenyl)prop-2-enoic acid
Formula	C₉ H₈ O₃
Molecular Weight	164.158
Type	NON-POLYMER
Isomeric SMILES	c1ccc(c(c1)\C=C\C(=O)O)O
InChI	InChI=1S/C9H8O3/c10-8-4-2-1-3-7(8)5-6-9(11)12/h1-6,10H,(H,11,12)/b6-5+
InChIKey	PMOWTIHVNWZYFI-AATRIKPKSA-N

Chemical Details
Formal Charge	0
Atom Count	20
Chiral Atom Count	0
Bond Count	20
Aromatic Bond Count	6

Drug Info: DrugBank

DrugBank ID	DB01650
Name	trans-2-hydroxycinnamic acid
Groups	experimental
Synonyms	o-hydroxy-trans-cinnamic acid (E)-3-(2-Hydroxyphenyl)-2-propenoic acid trans-2-hydroxycinnamic acid (2E)-3-(2-hydroxyphenyl)prop-2-enoic acid o-Coumaric acid trans-2-Hydroxycinnamate 2-Hydroxycinnamate trans-o-hydroxycinnamic acid (2E)-3-(2-hydroxyphenyl)-2-propenoic acid (E)-o-hydroxycinnamic acid 2-Coumarate 2-Coumaric acid
Categories	OAT3/SLC22A8 Inhibitors
CAS number	614-60-8

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Major NAD(P)H-flavin oxidoreductase	MTHPIIHDLENRYTSKKYDPSKKVSQEDLAVLLEALRLSASSINSQPWKF...	unknown
Solute carrier family 22 member 8	MTFSEILDRVGSMGHFQFLHVAILGLPILNMANHNLLQIFTAATPVHHCR...	unknown	inhibitor

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682