Chemical Component Summary

NameNITROGEN DIOXIDE
Identifiersn/a
FormulaN O2
Molecular Weight46.005
TypeNON-POLYMER
Isomeric SMILESN(=O)[O]
InChIInChI=1S/HNO2/c2-1-3/h(H,2,3)
InChIKeyIOVCWXUNBOPUCH-UHFFFAOYSA-N

Chemical Details

Formal Charge0
Atom Count3
Chiral Atom Count0
Bond Count2
Aromatic Bond Count0

Drug Info: DrugBank

DrugBank IDDB09112 
NameNitrous acid
Groups
  • approved
  • investigational
DescriptionNitrous acid (as sodium nitrite) is used as part of an intravenous mixture with sodium thiosulfate to treat cyanide poisoning. It is on the World Health Organization's List of Essential Medicines, a list of the most important medications needed in a basic health system. There is also research to investigate its applicability towards treatments for heart attacks, brain aneurysms, pulmonary hypertension in infants, and Pseudomonas aeruginosa infections.
Synonyms
  • dioxonitric acid
  • nitrosyl hydroxide
  • hydroxidooxidonitrogen
  • Potassium nitrite
  • Sodium nitrite
Brand Names
  • Wakefern Enamel Guard
  • CVS Pharmacy Enamel Guard
  • Sodium Nitrite Injection, USP
  • Nithiodote
  • Sodium Nitrite
IndicationFor sequential use with sodium thiosulfate for the treatment of acute cyanide poisoning that is judged to be life-threatening [FDA Label].
Categories
  • Acids
  • Acids, Noncarboxylic
  • Anions
  • Antidotes
  • Compounds used in a research, industrial, or household setting
ATC-CodeV03AB08
CAS number7782-77-6

Drug Targets

NameTarget SequencePharmacological ActionActions
Hemoglobin subunit alphaMVLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLS...unknownoxidizer
Hemoglobin subunit betaMVHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLS...unknownoxidizer
MyoglobinMGLSDGEWQLVLNVWGKVEADIPGHGQEVLIRLFKGHPETLEKFDKFKHL...unknownoxidizer
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource NameReference
PubChem 3032552