4AX

(R)-4-AMINO-ISOXAZOLIDIN-3-ONE

Find entries where: 4AX

is present as a standalone ligand in 2 entries

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Chemical Component Summary
Name	(R)-4-AMINO-ISOXAZOLIDIN-3-ONE
Identifiers	(4R)-4-amino-1,2-oxazolidin-3-one
Formula	C₃ H₆ N₂ O₂
Molecular Weight	102.092
Type	NON-POLYMER
Isomeric SMILES	C1[C@H](C(=O)NO1)N
InChI	InChI=1S/C3H6N2O2/c4-2-1-7-5-3(2)6/h2H,1,4H2,(H,5,6)/t2-/m1/s1
InChIKey	DYDCUQKUCUHJBH-UWTATZPHSA-N

Chemical Details
Formal Charge	0
Atom Count	13
Chiral Atom Count	1
Bond Count	13
Aromatic Bond Count	0

Drug Info: DrugBank

DrugBank ID	DB00260
Name	Cycloserine
Groups	approved
Description	Antibiotic substance produced by Streptomyces garyphalus.
Synonyms	Cycloserinum DCS α-Cycloserine Cicloserina D-(+)-cycloserine Cyclosérine cyclo-D-Serine Orientomycin alpha-Cycloserine (+)-4-amino-3-isoxazolidinone D-Cycloserine (+)-cycloserine Cycloserine D-4-amino-3-isoxazolidone D-4-amino-3-isoxazolidinone
Brand Names	Cycloserine Seromycin Seromycin Cap 250mg
Indication	Used in combination with up to 5 other drugs as a treatment for Mycobacterium avium complex (MAC) and is also used to treat tuberculosis (TB).
Categories	Amino Acids Amino Acids, Neutral Amino Acids, Peptides, and Proteins Anti-Bacterial Agents Anti-Infective Agents Anti-Infective Agents, Urinary Antibiotics, Antitubercular Antiinfectives for Systemic Use Antimetabolites Antimycobacterials Drugs for Treatment of Tuberculosis Isoxazoles Neurotoxic agents Noxae Oxazoles Oxazolidinones Toxic Actions
ATC-Code	J04AB01
CAS number	68-41-7

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
D-alanine--D-alanine ligase A	MEKLRVGIVFGGKSAEHEVSLQSAKNIVDAIDKSRFDVVLLGIDKQGQWH...	unknown	inhibitor
Alanine racemase	MAVTPISLTPGVLAEALVDLGAIEHNVRLLCEQARGAQVMAVVKADGYGH...	unknown	inhibitor
Aromatic-L-amino-acid decarboxylase	MNASEFRRRGKEMVDYMANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEP...	unknown	inhibitor
Proton-coupled amino acid transporter 2	MSVTKSTEGPQGAVAIKLDLMSPPESAKKLENKDSTFLDESPSESAGLKK...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682