5HU

5-HYDROXYMETHYLURIDINE-2'-DEOXY-5'-MONOPHOSPHATE

Find entries where: 5HU

is present as a standalone ligand in 4 entries

is present in a polymer sequence 6 entries

Find related ligands:

Similar Ligands (Stereospecific)

Similar Ligands (Quick Screen)

Toggle Hydrogen Toggle Labels

Chemical Component Summary
Name	5-HYDROXYMETHYLURIDINE-2'-DEOXY-5'-MONOPHOSPHATE
Identifiers	[(2R,3S,5R)-3-hydroxy-5-[5-(hydroxymethyl)-2,4-dioxo-pyrimidin-1-yl]oxolan-2-yl]methyl dihydrogen phosphate
Formula	C₁₀ H₁₅ N₂ O₉ P
Molecular Weight	338.208
Type	DNA LINKING
Isomeric SMILES	C1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=O)CO)COP(=O)(O)O)O
InChI	InChI=1S/C10H15N2O9P/c13-3-5-2-12(10(16)11-9(5)15)8-1-6(14)7(21-8)4-20-22(17,18)19/h2,6-8,13-14H,1,3-4H2,(H,11,15,16)(H2,17,18,19)/t6-,7+,8+/m0/s1
InChIKey	WEBVWKFGRVLCNS-XLPZGREQSA-N

Chemical Details
Formal Charge	0
Atom Count	37
Chiral Atom Count	3
Bond Count	38
Aromatic Bond Count	0

Drug Info: DrugBank

DrugBank ID	DB03846
Name	2'-deoxy-5-(hydroxymethyl)uridine 5'-(dihydrogen phosphate)
Groups	experimental
Synonyms	5-hydroxymethyluridine-2'-deoxy-5'-monophosphate 2'-deoxy-5-(hydroxymethyl)uridine 5'-(dihydrogen phosphate)

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Thymidylate kinase	MLIAIEGVDGAGKRTLVEKLSGAFRAAGRSVATLAFPRYGQSVAADIAAE...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682