Chemical Component Summary | |
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Name | PF-3758309 |
Identifiers | ~{N}-[(1~{S})-2-(dimethylamino)-1-phenyl-ethyl]-6,6-dimethyl-3-[(2-methylthieno[3,2-d]pyrimidin-4-yl)amino]-1,4-dihydropyrrolo[3,4-c]pyrazole-5-carboxamide |
Formula | C25 H30 N8 O S |
Molecular Weight | 490.624 |
Type | NON-POLYMER |
Isomeric SMILES | Cc1nc2ccsc2c(n1)Nc3c4c([nH]n3)C(N(C4)C(=O)N[C@H](CN(C)C)c5ccccc5)(C)C |
InChI | InChI=1S/C25H30N8OS/c1-15-26-18-11-12-35-20(18)23(27-15)29-22-17-13-33(25(2,3)21(17)30-31-22)24(34)28-19(14-32(4)5)16-9-7-6-8-10-16/h6-12,19H,13-14H2,1-5H3,(H,28,34)(H2,26,27,29,30,31)/t19-/m1/s1 |
InChIKey | AYCPARAPKDAOEN-LJQANCHMSA-N |
Chemical Details | |
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Formal Charge | 0 |
Atom Count | 65 |
Chiral Atom Count | 1 |
Bond Count | 69 |
Aromatic Bond Count | 21 |
Drug Info: DrugBank
DrugBank ID | DB11775 |
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Name | PF-03758309 |
Groups | investigational |
Description | PF-03758309 has been used in trials studying the treatment of Advanced Solid Tumors. |
Synonyms |
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Categories | p21-Activated Kinases, antagonists & inhibitors |
CAS number | 898044-15-0 |
Related Resource References
Resource Name | Reference |
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Pharos | CHEMBL3128043 |
PubChem | 25227462 |
ChEMBL | CHEMBL3128043 |
ChEBI | CHEBI:93751 |