8OG

8-OXO-2'-DEOXY-GUANOSINE-5'-MONOPHOSPHATE

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is present as a standalone ligand in 20 entries

is present in a polymer sequence 246 entries

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Chemical Component Summary
Name	8-OXO-2'-DEOXY-GUANOSINE-5'-MONOPHOSPHATE
Synonyms	8-OXO-7,8-DIHYDRO-2'-DEOXY-GUANOSINE-5'-MONOPHOSPHATE
Identifiers	[(2R,3S,5R)-5-(2-amino-6,8-dioxo-1,7-dihydropurin-9-yl)-3-hydroxy-oxolan-2-yl]methyl dihydrogen phosphate
Formula	C₁₀ H₁₄ N₅ O₈ P
Molecular Weight	363.221
Type	DNA LINKING
Isomeric SMILES	C1[C@@H]([C@H](O[C@H]1N2C3=C(C(=O)NC(=N3)N)NC2=O)COP(=O)(O)O)O
InChI	InChI=1S/C10H14N5O8P/c11-9-13-7-6(8(17)14-9)12-10(18)15(7)5-1-3(16)4(23-5)2-22-24(19,20)21/h3-5,16H,1-2H2,(H,12,18)(H2,19,20,21)(H3,11,13,14,17)/t3-,4+,5+/m0/s1
InChIKey	AQIVLFLYHYFRKU-VPENINKCSA-N

Chemical Details
Formal Charge	0
Atom Count	38
Chiral Atom Count	3
Bond Count	40
Aromatic Bond Count	0

Drug Info: DrugBank

DrugBank ID	DB02023
Name	8-oxo-dGMP
Groups	experimental
Synonyms	8-oxo-dGMP 2'-deoxy-7,8-dihydro-8-oxoguanosine 5'-monophosphate 8-oxo-2'-deoxyguanosine-5'-monophosphate 8-hydroxydeoxyguanosine 5'-monophosphate 8-OH-Dgmp 2'-deoxy-7,8-dihydro-8-oxo-5'-guanylic acid
Categories	Guanine Nucleotides Heterocyclic Compounds, Fused-Ring Nucleic Acids, Nucleotides, and Nucleosides Nucleotides Purine Nucleotides Purines Ribonucleotides
CAS number	127027-50-3

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
8-oxo-dGTP diphosphatase	MKKLQIAVGIIRNENNEIFITRRAADAHMANKLEFPGGKIEMGETPEQAV...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682