8W7

(3S)-3-[4-({4-[(morpholin-4-yl)methyl]phenyl}methoxy)-1-oxo-1,3-dihydro-2H-isoindol-2-yl]piperidine-2,6-dione


Toggle HydrogenToggle Labels

Chemical Component Summary

Name(3S)-3-[4-({4-[(morpholin-4-yl)methyl]phenyl}methoxy)-1-oxo-1,3-dihydro-2H-isoindol-2-yl]piperidine-2,6-dione
Identifiers(3~{S})-3-[7-[[4-(morpholin-4-ylmethyl)phenyl]methoxy]-3-oxidanylidene-1~{H}-isoindol-2-yl]piperidine-2,6-dione
FormulaC25 H27 N3 O5
Molecular Weight449.499
TypeNON-POLYMER
Isomeric SMILESc1cc2c(c(c1)OCc3ccc(cc3)CN4CCOCC4)CN(C2=O)[C@H]5CCC(=O)NC5=O
InChIInChI=1S/C25H27N3O5/c29-23-9-8-21(24(30)26-23)28-15-20-19(25(28)31)2-1-3-22(20)33-16-18-6-4-17(5-7-18)14-27-10-12-32-13-11-27/h1-7,21H,8-16H2,(H,26,29,30)/t21-/m0/s1
InChIKeyIXZOHGPZAQLIBH-NRFANRHFSA-N

Chemical Details

Formal Charge0
Atom Count60
Chiral Atom Count1
Bond Count64
Aromatic Bond Count12

Drug Info: DrugBank

DrugBank IDDB12101 
NameIberdomide
Groups investigational
DescriptionIberdomide (CC-220) has been used in trials studying the treatment of Systemic Lupus Erythematosus.
Synonyms
  • (S)-3-(4-((4-(Morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
  • 2,6-Piperidinedione, 3-(1,3-dihydro-4-((4-(4-morpholinylmethyl)phenyl)methoxy)-1-oxo-2H-isoindol-2-yl)-, (3S)-
  • Iberdomide
Categories
  • Acids, Carbocyclic
  • Heterocyclic Compounds, Fused-Ring
  • Imides
  • Isoindoles
  • Oxazines
CAS number1323403-33-3

Related Resource References

Resource NameReference
Pharos CHEMBL3989927
PubChem 67335295
ChEMBL CHEMBL3989927